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Khai Beng Chong

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Articles

Pain Signaling by GPCRs and RTKs

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By Claudio Vicini, Terry Kenakin, Olivier J. Manzoni, Khai Beng Chong
| ScienceDirect Verified
Section snippets Chronic pain: mechanisms, challenges, and therapeutic advances Chronic pain (see Glossary) is common, debilitating, and poorly understood [1,2]. Existing therapies are often ineffective and have life-threatening or fatal side effects. This review highlights recent advances in our understanding of the mechanisms by which receptors signal chronic pain and discusses how this deepened knowledge can lead to more effective and safer treatments for chronic pain.
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