Kouloud Zayoud on Muck Rack

Kouloud Zayoud

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Articles

Supplementation with nicotinamide limits accelerated aging in affected individuals with cockayne syndrome and restores antioxidant defenses

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By Asma Chikhaoui, Kouloud Zayoud, Ichraf Kraoua, Sami Bouchoucha
| Aging
Cockayne syndrome (CS) is a segmental progeroid syndrome characterized by defects in the DNA excision repair pathway, predisposing to neurodegenerative manifestations. It is a rare genetic disorder and an interesting model for studying premature aging. Oxidative stress and autophagy play an important role in the aging process.
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