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Articles by Kui Yang
Strain-induced faceting of Ti 4 O 7 for active chlorine electrosynthesis
Abstract Electrosynthesis of bulk chemicals such as active chlorine depends on the most reactive crystal facets, yet these facets are often thermodynamically disfavored during crystal growth. Here, we present a faceting strategy that integrates 3D printing with electric field inducement to reorient triclinic Ti4O7, realizing a dominant facet transition from (1 − 2 0) to high-energy (0 2 − 2) by storing and releasing strain energy to promote the preferential growth of crystal.
Full article: Microbial metabolite trimethylamine-N-oxide facilitates colorectal inflammation-cancer transformation by blocking lysosomal degradation of Wnt signaling
Abstract Chronic inflammation is closely related to the occurrence and development of many tumors, including colorectal cancer (CRC), a typical inflammation-dependent cancer. The gut bacteria and their metabolites, as signaling molecules or substrates of metabolic processes, have attracted increasing attention during the colorectal inflammation-cancer transformation process.
Red blood cell distribution width-to-albumin ratio and postoperative pleural effusion risk after gastrectomy for esophagogastric junction adenocarcinoma: a retrospective study
Abstract Background: Postoperative pleural effusions (PPE) are common complications following gastrectomy, particularly in patients diagnosed with Siewert type II/III esophagogastric cancer. The red blood cell distribution width-to-albumin ratio (RAR) is a marker indicative of systemic inflammation and nutritional status.
MYB Proto-Oncogene Like 2 Promotes the Growth of Renal Carcinoma by Attenuating Endoplasmic Reticulum Stress and Activating Lipid Rafts
Ayuda Buscar en la ayuda Buscar en la ayuda MYB Proto-Oncogene Like 2 Promotes the Growth of Renal Carcinoma by Attenuating Endoplasmic Reticulum Stress and Activating Lipid Rafts Xiaoxi Zhang [1] ; Baixin Liu [2] ; Chunlai Cheng [1] ; Kui Yang [1] ; Dailong Li [1] ; Yuan Che [1] [1] Oncology, General Hospital of The Yangtze River Shipping, 430000 Wuhan, Hubei, China [2] Urology, General Hospital of The Yangtze River Shipping, 430000 Wuhan, Hubei, China Localización: Archivos españoles de...
The Construction of a Library of Nanozyme with High Nitrogen Content for Efficient Antibacterial Applications
Conflict of Interest The authors declare no conflict of interest. Supporting Information Filename Description smll202500558-sup-0001-SuppMat.pdf1.2 MB Supporting Information References 1, , , Chem. Rev. 2019, 119, 4357. 2a) , , Small 2023, 19, 2302640; b) , , , , , , , , , ACS Appl. Bio Mater. 2023, 6, 3577. 3a) , , , , , , , , , , , , Small 2024, 20, 2309366; b) , , , , , Chem. Eng. J. 2024, 495, 153314. 4, , , , , , , , , Angew. Chem., Int. Ed. 2021, 60, 1227. 5, , , , , , , ACS Nano 2022, 16, 855.
Development of ferret immune repertoire reference resources and single-cell-based high-throughput profiling assays
Abstract Domestic ferrets (Mustela putorius furo) are important for modeling human respiratory diseases. However, ferret B and T cell receptors have not been completely identified or annotated, limiting immune repertoire studies. Here we performed long read transcriptome sequencing of ferret splenocyte and lymph node samples to obtain over 120,000 high-quality full-length immunoglobin (Ig) and T cell receptor (TCR) transcripts.
Scene Measurement Method Based on Fusion of Image Sequence and Improved LiDAR SLAM
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4‐Octyl itaconate blocks GSDMB‐mediated pyroptosis and restricts inflammation by inactivating granzyme A
1 INTRODUCTION Pyroptosis, an inflammatory form of programmed cell death that releases substantial cellular contents to activate fierce inflammation, is vital for immune defence against endogenous dangers and pathogenic infections.1 Pyroptosis is mediated by gasdermin (GSDM) family proteins that consist of an N-terminal pore-forming domain (GSDM-NT), a C-terminal autoinhibitory domain (GSDM-CT) and an interdomain linker.2 The GSDMs, except for DFNB59 (PJVK), share a similar activation...
Prognostic hypoxia-angiogenesis-related gene signature in hepatocellul
Back to Journals » Journal of Inflammation Research » Volume 17 Authors Wang S , Ye W, Yang K , Lv X , Luan J Received 1 July 2024 Accepted for publication 19 August 2024 Published 27 August 2024 Volume 2024:17 Pages 5663—5683 DOI https://doi.org/10.2147/JIR.S476388 Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 2 Editor who approved publication: Professor Ning Quan Sheng Wang,1– 3,* Wufei Ye,1,3,* Kui Yang,1,3 Xiongwen Lv,2 Jiajie Luan1,3...
Facile preparation of high-efficiency peroxidase mimics: Modulation catalytic microenvironment of LDH nanozymes through defect engineering induced by amino acids intercalation
Facile preparation of high-efficiency peroxidase mimics: Modulation catalytic microenvironment of LDH nanozymes through defect engineering induced by amino acids intercalation Nanozymes have gained much attention as the replacement of natural enzymes duo to their unique advantages. Two-dimensional layered double hydroxide (LDH) nanomaterials with high physicochemical plasticity are emerging as main forces for the construction of nanozymes.
Adaptive Intervention Algorithms for Advanced Driver Assistance Systems
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Adsorption/Desorption Performances of Simulated Radioactive Nuclide Cs+ on the Zeolite-Rich Geopolymer from the Hydrothermal Synthesis of Fly Ash
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Multi-target distortion correction in 3D shape from polarization using a monocular camera system by deep neural networks
The shape from polarization is a noncontact 3D imaging method that shows great potential, but its application is limited by the monocular camera system and surface integration algorithm. This Letter proposes a novel, to the best of our knowledge, method that employs deep neural networks to enhance multi-target 3D reconstruction, making a significant advancement in the field.
Shifting Emphasis from Electro- to Catalytically Active Sites: Effects of Pore Size of Flow-Through Anodes on Water Purification
Download Hi-Res ImageDownload to MS-PowerPointCite This:Environ. Sci. Technol. 2023, XXXX, XXX Terms & Conditions Most electronic Supporting Information files are available without a subscription to ACS Web Editions. Such files may be downloaded by article for research use (if there is a public use license linked to the relevant article, that license may permit other uses).
R-MFNet: Analysis of Urban Carbon Stock Change against the Background of Land-Use Change Based on a Residual Multi-Module Fusion Network
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Effect of substitution groups on the homopolymerization activity of methyl aryl diallyl ammonium chloride
RESEARCH ARTICLE Xu Jia and Meiying Wang contributed equally to this work. Abstract Dimethyl diallyl ammonium chloride (DMDAAC), recognized for its high positive charge density among the several diallyl quaternary ammonium cationic monomers, has been constrained in lipophilic applications by its structure. In this article, benzyl, p-methylbenzyl, and p-nitrobenzyl were introduced as structural modifications of DMDAAC to compensate for this.
eBay’s Blazingly Fast Billion-Scale Vector Similarity Engine
Introduction Often, ecommerce marketplaces provide buyers with listings similar to those previously visited by the buyer, as well as a personalized shopping experience based on profiles, past shopping histories and behavior signals such as clicks, views and additions to cart. These are vital to the shopping experience, and so it’s equally vital that we continuously improve accuracy and robustness in scalability and performance.
Carbon monoxide therapy: a promising strategy for cancer
Carbon monoxide therapy: a promising strategy for cancer Yan Wang, Jingjing Chai, Kui Yang, Junfei Zhu, Jiajie Luan and Yu Tian Abstract Cancer is one of the acute life-threatening diseases endangering the whole of humanity. The treatment modalities for cancer are various. However, in most cases, a single treatment choice exerted multiple side effects, poor targeting, and ineffective treatment.
MnO2-Based nanosystems for cancer therapy
MnO2-Based nanosystems for cancer therapy Jia Wen, †a Kui Yang †b and Shiguo Sun *c Author affiliations * Corresponding authors a Key Laboratory of Pharmaceutical Quality Control of Hebei Province, College of Pharmaceutical Science, Hebei University, Baoding 071002, China b Laboratory of Medicinal Chemistry and Molecular Diagnosis of the Ministry of Education, Key Laboratory of Chemical Biology of Hebei Province, College of Chemistry and Environmental Science, Hebei University, Baoding...
Host-guest interaction based supramolecular photodynamic therapy systems: a promising candidate in the battle against cancer
Host–guest interaction based supramolecular photodynamic therapy systems: a promising candidate in the battle against cancer Kui Yang, †*a Zhihua Zhang,†b Jie Du,a Wei Li *a and Zhichao Pei *c Author affiliations * Corresponding authors a Laboratory of Medicinal Chemistry and Molecular Diagnosis of the Ministry of Education, Key Laboratory of Chemical Biology of Hebei Province, College of Chemistry and Environmental Science, Hebei University, Baoding 071002, P. R.
The Coxsackievirus and Adenovirus Receptor, a Required Host Factor for Recovirus Infection, Is a Putative Enteric Calicivirus Receptor
Virus-Cell Interactions | Spotlight Tibor Farkas, Kui Yang, Jacques Le Pendu, Joel D. Baines, Rhonda D. Cardin Julie K. Pfeiffer, Editor DOI: 10.1128/JVI.00869-19 ABSTRACT Human norovirus (HuNoV) is a leading cause of acute gastroenteritis in both developed and developing countries. Studies of HuNoV host cell interactions are limited by the lack of a simple, robust cell culture system.
Screening of Polysorbate-80 Composition by High Resolution Mass Spectrometry with Rapid H/D Exchange
Download Hi-Res ImageDownload to MS-PowerPointCite This:Anal. Chem. 2019, XXXX, XXX RETURN TO ARTICLES ASAPPREVArticleNEXT Kui Yang* Kui Yang Division of Pharmaceutical Analysis, Office of Testing and Research, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, St. Louis, Missouri 63110, United States *E-mail: . Phone: +1-314-539-3804.
Recent Advances in the Development of Rotaxanes and Pseudorotaxanes based on Pillar[n]arenes: From Construction to Application
Recent Advances in the Development of Rotaxanes and Pseudorotaxanes based on Pillar[n]arenes: From Construction to Application Mechanically inter-locked molecules (MIMs) mainly including rotaxanes and pseudorotaxanes have attracted enormous attentions for the fabrication of molecular machines, which can be constructed by macrocyclic molecules as the main building blocks through the host-guest complexation.
Supramolecular Delivery Systems Based on Pillararenes
Supramolecular delivery systems (SDSs), fabricated via molecular assembly that conveniently allows for integration of multiple functions in a single system and structural diversity of the systems, are a very active research area due to their huge potentials in biomedical applications including drug delivery, cell imaging, diagnosis, release monitoring, etc..
Deeply seeing through highly turbid water by active polarization imaging
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A supramolecular hybrid material constructed from pillar[6]arene-based host-guest complexation and ZIF-8 for targeted drug delivery
A novel supramolecular hybrid material ZIF-8@DOX@WP6@G constructed from the host-guest complexation between carboxylated pillar[6]arene (WP6) and galactose derivative (G), and doxorubicin (DOX)-loaded ZIF-8 has been synthesized for targeted drug delivery. The results showed that ZIF-8@DOX@WP6@G not only maintained the pH-sensitive drug release property of ZIF-8 but also exhibited excellent water dispersibility and selective toxicity for hepatoma cancer cells due to the assembly of WP6 and G.
Cytochrome c is an oxidative stress-activated plasmalogenase that cleaves plasmenylcholine and plasmenylethanolamine at the sn-1 vinyl ether linkage
Plasmalogens are phospholipids critical for cell function and signaling that contain a vinyl ether linkage at the sn-1 position and are highly enriched in arachidonic acid (AA) at the sn-2 position. However, the enzyme(s) responsible for the cleavage of the vinyl ether linkage in plasmalogens has remained elusive.
A supramolecular photosensitizer system based on the host-guest complexation between water-soluble pillar[6]arene and methylene blue for durable photodynamic therapy
A supramolecular photosensitizer system WP6-MB was synthesized based on water-soluble pillar[6]arene and photosensitizer methylene blue (MB) via host-guest interaction. MB can complex with WP6 directly with high complex constant without further modification. In particular, WP6-MB can reduce the dark toxicity of MB remarkably.
Cytochrome c is an oxidative stress-activated plasmalogenase that cleaves plasmenylcholine and plasmenylethanolamine at the sn-1 vinyl-ether linkage
Plasmalogens are phospholipids critical for cell function and signaling that contain a vinyl–ether linkage at the sn-1 position and are highly enriched in arachidonic acid (AA) at the sn-2 position. However, the enzyme(s) responsible for the cleavage of the vinyl ether linkage in plasmalogens has remained elusive.
Caveolin-1 regulates lipid droplet metabolism in endothelial cells via autocrine prostacyclin-stimulated, cAMP-mediated lipolysis
Lipid droplets (LD) are dynamic organelles involved in intracellular lipid metabolism in almost all eukaryotic cells, and LD-associated proteins tightly regulate their dynamics. One LD coat protein is caveolin-1 (Cav-1), an essential component for caveola assembly in highly differentiated cells, including adipocytes, smooth muscle cells, and endothelial cells (EC). However, the role of Cav-1 in LD dynamics is unclear. Here we report that EC lacking Cav-1 exhibit impaired LD formation.
Heart failure-induced activation of phospholipase iPLA2γ generates hydroxyeicosatetraenoic acids opening the mitochondrial permeability transition pore
Congestive heart failure typically arises from cardiac myocyte necrosis/apoptosis, associated with the pathological opening of the mitochondrial permeability transition pore (mPTP). mPTP opening decreases the mitochondrial membrane potential leading to the activation of Ca2+-independent phospholipase A ? (iPLA ?) and the production of downstream toxic metabolites.
Caveolin-1 regulates lipid droplet metabolism in endothelial cells via autocrine prostacyclin stimulated cAMP-mediated lipolysis
Lipid droplets (LD) are dynamic organelles involved in intracellular lipid metabolism in almost all eukaryotic cells and LD associated proteins tightly regulate their dynamics. One LD coat proteins is caveolin-1 (Cav-1), an essential component for caveolae assembly in highly differentiated cells including adipocytes, smooth muscle cells and endothelial cells (EC). However, the role of Cav-1 in LD dynamics is unclear. Here, we report that EC lacking Cav-1 exhibit impaired LD formation.
Heart failure-induced activation of phospholipase iPLA2γ generates hydroxyeicosatetraenoic acids opening the mitochondrial permeability transition pore
Congestive heart failure typically arises from cardiac myocyte necrosis/apoptosis, associated with the pathological opening of the mitochondrial permeability transition pore (mPTP). mPTP opening decreases the mitochondrial membrane potential leading to the activation of Ca2+-independent phospholipase A ? (iPLA ?) and the production of downstream toxic metabolites.
Diverse gatekeepers for mesoporous silica nanoparticle based drug delivery systems
Conventional cancer chemotherapy is often associated with toxicity issues. Thus, new drug delivery systems (DDSs) are developed as alternatives owing to their potential to selectively target affected cells while sparing normal tissues. Among them, noninvasive and biocompatible mesoporous silica nanoparticle (MSN)-based targeted DDSs have developed rapidly.
Synergistic and Targeted Drug Delivery Based on Nano-CeO2 Capped with Galactose Functionalized Pillar[5] arene via Host-Guest Interactions
X. Wu, Y. Zhang, Y. Lu, S. Pang, K. Yang, Z. Tian, Y. Pei, Y. Qu, F. Wang and Z. Pei, J. Mater. Chem. B, 2017, Accepted Manuscript , DOI: 10.1039/C7TB00752C If you are not the author of this article and you wish to reproduce material from it in a third party non-RSC publication you must formally request permission using RightsLink. Go to our Instructions for using RightsLink page for details.
Recent advances in pillar[n]arenes: synthesis and application based on host-guest interactions
Pillar[n]arenes (n = 5-15) are a novel class of macrocyclic molecules with hydroquinone as repeat unit and linked by methylene bridges at para-positions. Introduced by T. Ogoshi for the first time in 2008, pillararenes have attracted increasing interest and been widely studied during the last eight years, due to their unique structural advantages as host molecules, such as symmetrical rigid architecture, electron-rich cavities and facile functional modification.
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