Kuiwu Yao

1 Introduction The diagnostic criterion for hypertension is defined as systolic blood pressure (SBP) values of at least 140 mmHg and/or diastolic blood pressure (DBP) values of at least 90 mmHg (Williams et al., 2018). In 2015, the global prevalence of hypertension was estimated to be 1.13 billion based on office blood pressure (BP) (NCD Risk Factor Collaboration, 2017). The prevalence of hypertension will continue to rise as populations age, adopt more sedentary lifestyles, and gain weight.

1. Introduction Heart failure is the end-stage of various heart diseases, and the number of patients with heart failure is increasing in the context of aging, with a 5-year survival rate comparable to malignant tumors (1). As one of the main symptoms of heart failure, decreased exercise tolerance seriously affects the quality of life and prognosis of patients (2, 3), which has become one of the focal areas of concern in heart failure treatment.

Peng-Chong Zhu1†, Jiayi Shen1†, Ren-Yi Qian1, Jian Xu1, Chong Liu1, Wu-Ming Hu1, Ying Zhang2 and Ling-Chun Lv1* 1Department of Cardiology, Lishui Hospital of Zhejiang University, The Fifth Affiliated Hospital of Wenzhou Medical University, Lishui Municipal Central Hospital, Lishui, China 2Department of Gynaecology and Obstetrics, The First Affiliated Hospital of Jiamusi University, Jiamusi, China Introduction: Tanshinone IIA (Tan IIA), the major active lipophilic ingredient of Radix Salviae...