Ruiying Wang
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Macrophage migration inhibitory factor in atrial fibrillation
Abstract Macrophage migration inhibitory factor (MIF) is a multifunctional upstream cytokine that has attracted increasing attention for its role in the initiation and perpetuation of atrial fibrillation (AF). This review systematically discusses the dual regulatory roles of MIF in AF and its potential as both a biomarker and a therapeutic target.
The accuracy of lipid accumulation product to predict metabolic syndrome in PCOS: a meta-analysis and comparative analysis with other indicators
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Abstract Background: The diagnosis of metabolic syndrome (MetS) in patients with polycystic ovary syndrome (PCOS) is complex. Various indicators are utilized to predict MetS in clinical practice. Nonetheless, there is ongoing debate regarding which indicator possesses a higher predictive value. This study examines the accuracy of the lipid accumulation product (LAP) in screening for MetS among patients with PCOS and compares it with other indicators.
By Tingting Liu Verified, Qi Cao, Ruiying Wang, Xinyu Qiao, Yuchan Zhong, Jiagui Liang, Wei Huang, Wenjie Bo, Huiqiao Lai
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Frontiers
CXCR5 + monocyte emigration impairs the radiation-induced antitumor immune response
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Abstract A substantial portion of patients experience radioresistance, which impedes clinical benefit. The radiation-induced ‘protumor’ immune response is previously demonstrated to limit antitumor efficacy. However, the detailed mechanism remains to be explored. In this study, we observe CXCR5+ monocytes are enriched in tumor upon radiation. CXCR5 expression on monocytes in host is induced by tumor-derived VEGF through PI3K/mTOR/HIF-1α axis.
By Rui Jia, Chen Chen, Jiahong Shi, Mengdi Huang, Yixin Wang, Jiahao Sun, Yihan Wang, Tingting Lv, Ruiying Wang, Junyi Zhang, Du Yang, Hanmin Tang, Jianan Li, Liuyi Yang, Renyi Ding, Wenhua Li, Haiyan Liu, Anjun Jiao, Lingyun Hui, Shan Huang, Mengjiao Cai, Chenchen He, Chen Lin Verified, Fei Wang, Jinlu Ma, Suxia Han, Yuzhu Hou, Yutiantian Lei, Peihai Cao, Qiuyu Mu, Dairu Hou, Mingjun Si, Ruishan Guo, Dingge Jiang, Yanxia Sui
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Nature
Verified
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