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Abstract Pathogen genomic analysis is central to tracking, understanding and containing outbreaks1,2,3,4,5,6,7,8,9,10,11,12,13, but the complexity and cost of state-of-the-art phylogenetic tools limit global access and impact. Here we introduce Delphy, an exact reformulation of Bayesian phylogenetics14,15,16,17 designed to transform its speed, scalability and accessibility while retaining Bayesian state-of-the-art accuracy.
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