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Kyli Berkley

As seen in: Nature, MDPI
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Articles

Cholesterol-targeting Wnt–β-catenin signaling inhibitors for colorectal cancer - Nature Chemical Biology

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By Julian Zalejski, Hale Hasdemir, Jiachen Sun, Ruicheng Shi, Kyli Berkley, Charles Delisle, Dominick Pierre-Jacques, Bo Wang, Vladimir Gevorgyan, Emad Tajkhorshid, Defne Gorgun Ozgulbas, Ahmed Aloulou, Pawanthi Buweneka
| Nature Verified
Abstract Most persons with colorectal cancer (CRC) carry adenomatous polyposis coli (APC) truncation leading to aberrant Wnt–β-catenin signaling; however, effective targeted therapy for them is lacking as the mechanism by which APC truncation drives CRC remains elusive.
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Targeting STAT3 for Cancer Therapy: Focusing on Y705, S727, or Dual Inhibition?

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By Kyli Berkley, Julian Zalejski, Ashutosh Sharma
| MDPI
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
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Targeting STAT3 for Cancer Therapy: Focusing on Y705, S727, or Dual Inhibition?

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By Julian Zalejski, Ashutosh Sharma, Kyli Berkley
| preprints.org
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