1 Introduction Hydrogels are often applied as tissue engineering scaffolds to mimic the extracellular matrix (ECM) due to their high water content, comparable mechanical properties to native tissues, biocompatibility, and ability to present bioactive cues to cells.[1] The biochemical and mechanical properties of hydrogels regulate cell adhesion, spreading, proliferation, and other aspects of cell fate.[2] Therefore, independent tuning of hydrogel properties is required to optimally control...