Leda Klouda on Muck Rack

Leda Klouda

As seen in: AIP Publishing
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Articles

Human pluripotent stem cell-derived cardiomyocytes align under cyclic strain when guided by cardiac fibroblasts

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By Dylan Mostert, Robert Passier, Bart Groenen, Leda Klouda
| AIP Publishing
Strain avoidance of CMs in the presence of cFBs is not mediated by paracrine signaling or N-cadherin We next asked what mechanisms are underlying the strain avoidance of CMs when in co-culture with a threshold value of cFBs. In particular, we wondered if the observed effect could be explained by paracrine signaling of the cFBs or by direct cell–cell communication via adherens junctional protein N-cadherin.
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