Lendület Laboratory

Loading metrics Open Access Peer-reviewed Research Article Citation: Jász A, Biró L, Buday Z, Király B, Szalárdy O, Horváth K, et al. (2025) Persistently increased post-stress activity of paraventricular thalamic neurons is essential for the emergence of stress-induced alterations in behaviour. PLoS Biol 23(1): e3002962. https://doi.org/10.1371/journal.pbio.3002962 Academic Editor: Heather A.

How does diversity in the organization of secretory machines determine properties of neurotransmitter release? In this issue of Neuron, Rebola et al. (2019) found that distinct nanoscale assemblies of Ca2+ channels and Munc13, not overall channel abundance, mediate differing release characteristics of two cerebellar synapses.

Unexpected experiences often lead to strong memories. A new study by Krabbe and Paradiso et al. shows that vasoactive intestinal peptide (VIP)-expressing interneurons of the basolateral amygdala control associative learning and memory formation by gating aversive stimuli scaled by their unexpectedness. Fig. 1: VIP interneurons act as a permissive gate on local BLA circuitry during associative fear learning. References 1. LeDoux, J. E. Annu. Rev. Neurosci. 23, 155–184 (2000). 2. Krabbe, S. et al. Nat. Neurosci.