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Leonardo Vasquez Camus

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Articles

Decoding the Escherichia coli epitranscriptome

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By Sebastián Riquelme-Barrios, Siobhan A. Cusack, Leonardo Vasquez Camus, Korinna Burdack
| BioRxiv
Abstract Modifications of RNA, known as the epitranscriptome, affect mRNA stability, translation, and splicing in eukaryotes and have implications for developmental processes, cancer, and viral infections. In prokaryotes, however, the landscape of the epitranscriptome is still poorly understood. To address this knowledge gap, we used direct RNA sequencing with Nanopore technology to study RNA modifications in the model bacterium Escherichia coli.
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