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Siobhan A. Cusack on Muck Rack

Siobhan A. Cusack

As seen in: BioRxiv
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Articles

Direct RNA sequencing of the Escherichia coli epitranscriptome uncovers alterations under heat stress

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By Sebastián Riquelme-Barrios, Siobhan A. Cusack, Korinna Burdack, Leonardo Vasquez-Camus
| BioRxiv
Abstract Modifications of RNA, known as the epitranscriptome, affect gene expression, translation, and splicing in eukaryotes, with implications for developmental processes, cancer, and viral infections. In prokaryotes, regulation at the level of the epitranscriptome is still poorly understood. Here, we used Nanopore direct RNA sequencing of Escherichia coli to study RNA modifications and their changes under heat stress.
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Decoding the Escherichia coli epitranscriptome

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By Sebastián Riquelme-Barrios, Siobhan A. Cusack, Leonardo Vasquez Camus, Korinna Burdack
| BioRxiv
Abstract Modifications of RNA, known as the epitranscriptome, affect mRNA stability, translation, and splicing in eukaryotes and have implications for developmental processes, cancer, and viral infections. In prokaryotes, however, the landscape of the epitranscriptome is still poorly understood. To address this knowledge gap, we used direct RNA sequencing with Nanopore technology to study RNA modifications in the model bacterium Escherichia coli.
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Probing the physiological role of the plastid outer-envelope membrane using the oemiR plasmid collection

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By Serena Schwenkert, Anna Pratt, Beata Szulc, Siobhan A. Cusack
| BioRxiv
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