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Leonardos Mageiros

As seen in: Nature, BioRxiv, medRxiv
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Articles

Interplay Between the Gut Microbiome and Typhoid Fever: Insights from Endemic Countries and a Controlled Human Infection Model

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By Philip Ashton, Leonardos Mageiros, James E. Meiring, Angeziwa Chunga Chirambo
| medRxiv
The authors have declared no competing interest. KA, SK, NRT, OS were funded by the Wellcome Trust (220540/Z/20/A). For the purpose of open access, the authors have applied a CC-BY public copyright licence to any author-accepted manuscript version arising from this submission. This research was funded by the Wellcome Trust (STRATAA grant number 106158/Z/14/Z, and core funding to the Wellcome Sanger Institute, grant number 206194) and the Bill & Melinda Gates Foundation (grant number OPP1141321).
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A two-hit epistasis model prevents core genome disharmony in recombining bacteria

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By Aidan Taylor, Koji Yahara, Ben Pascoe, Leonardos Mageiros
| BioRxiv
New Results doi: https://doi.org/10.1101/2021.03.15.435406 Abstract Recombination of short DNA fragments via horizontal gene transfer (HGT) can both introduce beneficial alleles and create genomic disharmony through negative epistasis. For non-core (accessory) genes, the negative epistatic cost is likely to be minimal because the incoming genes have not co-evolved with the recipient genome.
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Author Correction: Genome evolution and the emergence of pathogenicity in avian Escherichia coli

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By Leonardos Mageiros, Guillaume Meric, Ben Pascoe, Evangelos Mourkas
| Nature Verified
Correction to: Nature Communications https://doi.org/10.1038/s41467-021-20988-w, published online 3 February 2021. The original version of this Article contained errors related to phylogroup attribution of lineages ST-117, ST-657, ST-1163, ST-4673, ST-23, ST-88 and ST-2230. The ‘Results’ originally incorrectly read ‘Poultry isolates from our dataset (Supplementary Data 1) clustered within six out of the eight known E.
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