Li-Jin Chew

1. Introduction ICH is a devastating disorder characterized by formation of hematoma within the brain parenchyma, with possible blood extension into the ventricles (Qureshi et al., 2001; Ziai and Carhuapoma, 2018). ICH accounts for 15–20% of all strokes, with a disability rate of 70% and a mortality rate of over 50% annually (van Asch et al., 2010).

Introduction Oligodendrocyte progenitor cells (OPCs) are among the most abundant glial cells distributed throughout the brain. These cells are known for maintaining the myelination of the central nervous system throughout an individual’s lifespan (Dawson et al., 2003; Trotter et al., 2010; Richardson et al., 2011; Gallo and Deneen, 2014; Fernandez-Castaneda and Gaultier, 2016).

Yiting Zhou Jing Zhang* Department of Pharmacy, School of Medicine, Sir Run Run Shaw Hospital, Zhejiang University, Hangzhou, China This article reviews the role of neuronal activity in myelin regeneration and the related neural signaling pathways. The article points out that neuronal activity can stimulate the formation and regeneration of myelin, significantly improve its conduction speed and neural signal processing ability, maintain axonal integrity, and support axonal nutrition.