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Articles by Liangjun Chen
Brain contrastive modeling reveals depression subtypes with distinct treatment response and progression
Abstract Major Depressive Disorder (MDD) is highly heterogeneous, limiting treatment efficacy. Despite efforts to delineate patient heterogeneity through subtyping, current approaches remain limited by noise, lack of clinical applicability, and insufficient external validation. Crucially, they focus on subtyping while neglecting staging information (e.g., illness duration). We developed BrainCVAE, a contrastive variational autoencoder, to disentangle MDD-specific neural features.
Lewis Base-Mediated [3 + 3] Cycloaddition of N -2,2,2-Trifluoroethylisatin Ketimines with Diazo Esters: Synthesis of Trifluoromethyl-1,2,4-triazine-spirooxindoles Click to copy article link Article link copied!
Cite Jump to ExpandCollapse ArticleMarch 13, 2026 Lewis Base-Mediated [3 + 3] Cycloaddition of N-2,2,2-Trifluoroethylisatin Ketimines with Diazo Esters: Synthesis of Trifluoromethyl-1,2,4-triazine-spirooxindoles Click to copy article linkArticle link copied! Liangjun Chen Liangjun Chen Department of Medicinal Chemistry, School of Pharmacy, Hebei Medical University, Shijiazhuang 050017, China Fei Xu Fei Xu Department of Medicinal Chemistry, School of Pharmacy, Hebei Medical University,...
Theory‐Guided Design of Ru-NiFe Cathode Catalysts for Anion Exchange Membrane Water Electrolysis at Large Electrode Scale
Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement The data that support the findings of this study are available from the corresponding author upon reasonable request.
Two-dimensional Sub-stoichiometric Covalent Organic Frameworks: From Synthesis to Applications
Two-dimensional Sub-stoichiometric Covalent Organic Frameworks: From Synthesis to Applications Sub-stoichiometrically covalent organic frameworks (ss-COFs) are an emerging class of crystalline porous materials featuring periodic unreacted sites derived from organic building blocks. While maintaining the crystallinity, porosity, and stability of stoichiometric COFs, these frameworks exhibit enhanced functionality due to their uncondensed sites.
Noble Metal Nanoparticles Anchored on Transition Metal Phosphides for Effective pH‐Universal Hydrogen Evolution
1 Introduction Green hydrogen from water electrocatalysis, powered by intermittent renewable energy, has given significant opportunities to achieve the strategic goals of renewable energy storage and carbon neutrality.[1, 2] The hydrogen evolution reaction (HER) can be conducted in acidic, neutral, and alkaline conditions, which plays a crucial part in electrochemical water splitting and dominates the hydrogen production efficiency.[3, 4] However, although tremendous effectors have been made,...
Surface Expansion Regionalization of the Hippocampus in Early Brain Development
Abstract The hippocampal formation is implicated in a myriad of crucial functions, particularly centered around memory and emotion, with distinct subdivisions fulfilling specific roles. However, there is no consensus on the spatial organization of these subdivisions, given that the functional connectivity and gene expression-based parcellation along its longitudinal axis differs from the histology-based parcellation along its medial-lateral axis.
Development of an all-in-one real-time PCR assay for simultaneous detection of spotted fever group rickettsiae, severe fever with thrombocytopenia syndrome virus and hantaan virus prevalent in central China
Loading metrics Open Access Peer-reviewed Research Article ? This is an uncorrected proof. Citation: Wang C, Chen L, Li X, Gu J, Xiang Y, Fang L, et al. (2024) Development of an all-in-one real-time PCR assay for simultaneous detection of spotted fever group rickettsiae, severe fever with thrombocytopenia syndrome virus and hantaan virus prevalent in central China. PLoS Negl Trop Dis 18(7): e0012024.
Large-scale fabrication of ZIF-derived electrocatalysts toward industrial oxygen evolution
Large-scale fabrication of ZIF-derived electrocatalysts toward industrial oxygen evolution The laboratory-scale regarding catalyst synthesis is far from reaching the expectations of industrial-scale water electrolysis, and the bottleneck is the large-scale preparation of electrocatalysts.
Development of an all-in-one real-time PCR assay for simultaneous detection of spotted fever group rickettsiae, severe fever with thrombocytopenia syndrome virus and orthohantavirus hantanense prevalent in central China
The authors have declared no competing interest. Yes I confirm all relevant ethical guidelines have been followed, and any necessary IRB and/or ethics committee approvals have been obtained.
Thiol-Ene Click Reaction Modified Triazinyl-Based Covalent Organic Framework for Pb(II) Ion Effective Removal
Download Hi-Res ImageDownload to MS-PowerPointCite This:ACS Appl. Mater. Interfaces 2024, XXXX, XXX Terms & Conditions Most electronic Supporting Information files are available without a subscription to ACS Web Editions. Such files may be downloaded by article for research use (if there is a public use license linked to the relevant article, that license may permit other uses).
Analysis of Lung Microbiome in COVID-19 Patients during Time of Hospitalization
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Longitudinal development of the cerebellum in human infants during the first 800 days
Total Cerebellum M 137.9 a Statistically significant volumetric changes in these structures during these age ranges with p < 0.01 after Bonferroni correction. 47.1 a Statistically significant volumetric changes in these structures during these age ranges with p < 0.01 after Bonferroni correction. 19.2 a Statistically significant volumetric changes in these structures during these age ranges with p < 0.01 after Bonferroni correction.
Investigation of the strut‐and‐tie model of a single‐plane cable‐stayed bridge tower under vertical component of the cable force
Abstract The design of reinforcement of concrete pylons in cable-stayed bridges is a challenging task. Usually, only the influence of the strong horizontal component of the cable force is considered during the reinforcement design of the concrete tower, while the bursting forces caused by the vertical components of the cable forces are ignored. However, the latter is also an important factor for concrete cracking in bridge towers.
Substoichiometric 3D Covalent Organic Frameworks Based on Hexagonal Linkers
Download Hi-Res ImageDownload to MS-PowerPointCite This:J. Am. Chem. Soc.
Compressible AgNWs/Ti3C2TX MXene Aerogel-based Highly Sensitive Piezoresistive Pressure Sensor as Versatile Electronic Skins
Compressible AgNWs/Ti3C2TX MXene Aerogel-based Highly Sensitive Piezoresistive Pressure Sensor as Versatile Electronic Skins Wearable pressure sensor as electronic skins have been intensively studied, while versatile electronic skins stimulate the demands for highly sensitive piezoresistive sensing system over ultrawide pressure range. Herein, a wearable and flexible piezoresistive pressure sensor is developed by assembling a new type of composite aerogel in the sandwich structure.
The presence of SARS‐CoV‐2 RNA in the feces of COVID‐19 patients
Abstract In December 2019, coronavirus disease 2019 (COVID‐19), caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), emerged in Wuhan, China, and has spread globally. However, the transmission route of SARS‐CoV‐2 has not been fully understood. In this study, we aimed to investigate SARS‐CoV‐2 shedding in the excreta of COVID‐19 patients.
RNA based mNGS approach identifies a novel human coronavirus from two individual pneumonia cases in 2019 Wuhan outbreak
Skip to main content Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation Journal List Emerg Microbes Infect v.9(1); 2020 PMC7033720 As a library, NLM provides access to scientific literature. Inclusion in an NLM database does not imply endorsement of, or agreement with, the contents by NLM or the National Institutes of Health. Learn more about our disclaimer.
Fine-Tuning Solid-State Ordering and Thermoelectric Performance of Regioregular P3HT Analogues by Sequential Oxygen-Substitution on Carbon Atoms along the Alkyl Side Chains
Fine-Tuning Solid-State Ordering and Thermoelectric Performance of Regioregular P3HT Analogues by Sequential Oxygen-Substitution on Carbon Atoms along the Alkyl Side Chains Conjugated polymers in thin films tend to orient their backbones in respect to substrates through self-assembly when processed from a solution. Molecular packing orientation and crystallinity of polymer crystals have been found to play a critical role on their electrical performance.
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