1 Introduction Oligodendrocytes are differentiated from oligodendrocyte progenitors and are the myelinating cells of the central nervous system.[1, 2] Oligodendrogenesis at the developmental stage is associated with a group of disorders known as demyelinating diseases, such as periventricular leukomalacia and multiple sclerosis.[3] Therefore, understanding the regulatory mechanism of the proliferation and differentiation of OPCs is fundamental to treating these diseases.
