Linda Reilly on Muck Rack

Linda Reilly

As seen in: Nature, Philly Voice, Kirkus Reviews, The Delaware County Daily Times, The Trentonian, CrimeReads, Star Democrat, Times Herald (Norristown, PA), MyEasternShoreMD, European Journal of Vascular and Endovascular Surgery and
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Articles

A dihydrouracil CRBN ligand mitigates IMiD associated safety liabilities in heterobifunctional targeted protein degrader

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By Monica C. Rodrigo-Brenni, Ghaith M. Hamza, Natacha Bohin, Tomas Adomavicius, Angelo Andres, Ulf Börjesson, Gavin W. Collie, Frederik Eisele, Ning Gao, Christoph Grebner, Frida Gustafsson, Andreas Hock, Praveen Kumar, Xin Li Verified, Ruth MacDonald, Katja Madeyski-Bengtson, Eric Stefan Miele, Philip Nevin, Jeroen Overman, Fiona Pachl, Claudio Pathe, Matthew Perry, Christopher Phillips, Andy Pike, Ian Purvis, Timothy Rasmusson, Sophie Regan, Linda Reilly, Jonathan Rose, Jingwen Wang, Xiang Zhai, Iacovos N. Michaelides, Kevin Moreau, Jasper C. Komen, Stefan Blaho, Gian Marco De Donatis, Andrea Gohlke, Cecilia Kankkonen, Emilyanne Leonard, R. Ian Storer
| Nature Verified
Abstract Immunomodulatory imide drugs (IMiDs) like lenalidomide and pomalidomide are effective in treating multiple myeloma (MM) but pose hematotoxicity risks by degrading neosubstrates Ikaros (IKZF1) and Aiolos (IKZF3). When these IMiD scaffolds are integrated into proteolysis targeting chimeras (PROTACs), they can inadvertently lead to the degradation of these neosubstrates alongside the intended protein of interest (POI), raising safety concerns.
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Book Review: Cheddar Late Than Dead by Linda Reilly

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By Linda Reilly
| thebashfulbookworm.com
Cheddar Late Than Dead Series: Grilled Cheese Mysteries #2 by Linda Reilly Publication Date January 31, 2023 Published by Poisoned Pen Press Purchase Here Buy on Amazon US - Buy on Apple - Buy on Kobo - Buy on Google - Buy at Barnes and Noble - Buy on Waterstones - Buy on Audible - Buy on Amazon UK Goodreads Genres: Fiction / Mystery & Detective / Amateur Sleuth, Fiction / Mystery & Detective / Cozy / Culinary, Fiction / Small Town & Rural, Fiction / Women Pages: 384 Format: ARC ***I received...
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CHEDDAR LATE THAN DEAD

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By Linda Reilly, Michael D. Connelly, Kathy Reichs
| Kirkus Reviews Verified
by Linda Reilly ‧ The queen of grilled cheese proves for a third time that she’s also a pretty good detective. Carly’s Grilled Cheese Eatery is the place where Carly Hale serves up delicious and exotic sandwiches. Her latest customers are Dawn Chapin and Klarissa Taddeo, whom she remembers from high school. Klarissa is about to marry Tony Manous, but not all is moonlight and roses. She blames Dawn, her wedding planner, for not reserving a venue for her bridal shower on time.
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