Linying Huang

Abstract To describe the demographic and clinical characteristics of inpatients with corneal blindness in China and identify independent risk factors. This multicentre, retrospective, observational study was conducted by 16 clinical centres in 15 provincial-level administrative regions across China. Inpatients discharged with a primary diagnosis of corneal disease between January 1, 2019, and December 31, 2021, were included.

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1 Introduction Esophageal cancer is one of the most common malignancies and the sixth leading cause of cancer death globally. Its two histologic subtypes are esophageal adenocarcinoma (EAC) and esophageal squamous cell carcinoma (ESCC). In Eastern Asian, about 90% of esophageal cancer cases are ESCC.[1, 2] The prognosis of ESCC is poor since most patients were usually diagnosed at advanced disease stages.