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Linying Xie

As seen in: Nature, Frontiers, MDPI
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Articles

BRD9 recognizes lactate-induced H3K18 lactylation to drive oncogenic chromatin remodeling in hepatocellular carcinoma - Cell Death & Differentiation

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By Donglei Ji, Yanjie Jia, Ze Sun, Chunfeng Gao, Caroline Zeng, Chunyu Wang, Miaomiao Yu, Linying Xie, Wenju Zhang, Yameng Li, Yingying Liang, Bai Ji, Yanzhu Yue, Yahui Liu, Ming-Ming Zhou, Lei Zeng, Enwei Wei, Guanglei Shang
| Nature Verified
Abstract Histone lactylation couples glycolytic metabolism to oncogenic transcription, but its mechanistic readers remain poorly defined. Here, we identify bromodomain-containing protein 9 (BRD9) as a lactyl-lysine reader that links lactate-driven H3K18 lactylation (H3K18la) to chromatin remodeling in hepatocellular carcinoma (HCC). Clinically, elevated H3K18la levels correlate with poor HCC prognosis.
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Clinical effectiveness of scleral taping combined with perfluoropropane for complex retinal detachment

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By Xin Wang, Chen Li, Linlin Liu, Linying Xie, Yiping Jiang
| Frontiers
1The First Clinical Medical College of Gannan Medical University, Ganzhou, China 2The First Affiliated Hospital of Soochow University, Suzhou, China 3First Affiliated Hospital of Gannan Medical University, Ganzhou, China Purpose: This study evaluated the effectiveness of scleral taping combined with C3F8 gas filling for the management of complex retinal detachment (CRD) and to objectively assessed its clinical value.
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Effect of Sintering Process on Microstructure and Properties of (Zr0.2Ta0.2Ti0.2Cr0.2Hf0.2)Si2 High-Entropy Silicide Ceramics

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By Zihao Zhang, Mengtian Liang, Huaigan Yi, Linying Xie
| MDPI
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
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