Skip To Main Content
Yingying Liang on Muck Rack

Yingying Liang

As seen in: Nature, Wiley Online Library, MDPI, Biomed Central (BMC), Diagnostic Pathology, BioRxiv, Dialnet - Universidad de La Rioja, Academic Radiology
Is this you? As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work. Claim your profile

Get in touch with Yingying

Contact Yingying, search articles and posts on X, monitor coverage, and track replies from one place.

Learn more about Muck Rack

Actions

Share this page

Is this you?

As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.
Claim your profile

Articles

Pan-retinal pathology detection in oct scans integrating natural language synthesis with diagnostic annotation

|
By Wangting Li, Weihao Gao, LU CHEN, Dong Fang, Lujia Feng, Canfeng Huang, Jia Liang, Yingying Diao, Bingyu Bai, Ting Xie, Pengfeng Li, Huiyan Zheng, Weihua Yang, Xue Yao, Fang Li, Zheng Gong, Zhuo Deng, Wenyong Huang, Bing Zhang, Zixia Zhou, Li Cai, Hongchang Yang, Xiaoshan Fang, Yunxia Leng, Danna Chen, Yingying Liang, Xiaoyan Dou, Haoying Li, Gang Du, Yunwei Hu, Lan Ma, Wei Chi, Shaochong Zhang, Yijing Zhuang, Pengxue Wei, Xiangqing Hei, Xianling Tang, Zengfen Wu, Donghui Pu, Guangbing Zhong, Linyi Luo
| Nature Verified
Abstract While OCT is pivotal for macular disease diagnosis, its adoption in primary care is limited by AI systems that cannot simultaneously analyze multi-sectional scans across the full spectrum of maculopathies or generate diagnostically integrated reports. Here we present iOCT, an intelligent OCT analysis system that integrates a multi-level annotation framework with data distillation to enable automated multi-sectional scan analysis and comprehensive natural language report generation.
Open in Who Shared Issue with article?

Dual targeting of topoisomerase I and DNA G-quadruplexes enhances senescence and chemosensitivity in colorectal cancer - Communications Biology

|
By Yameng Li, Donglei Ji, Yanjie Jia, Yingying Liang, Enwei Wei, Chunfeng Gao, Yongqi Li, Caroline Zeng, Liping Wang, Chunyu Wang, Zhen Guo, Yiqun Zhang, Ming-Ming Zhou, Di Wu, Lei Zeng
| Nature Verified
Abstract Colorectal cancer (CRC) remains a therapeutic challenge due to chemoresistance that limits conventional treatment efficacy. We developed ZBH-01, a camptothecin derivative engineered to target both topoisomerase I (TOP1) and DNA G-quadruplexes (G4s). Unlike irinotecan (CPT-11), which requires metabolic activation, ZBH-01 directly stabilizes TOP1-DNA covalent complexes and preferentially binds the hTERT promoter G4, a regulator of telomere maintenance and oncogenic transcription.
Open in Who Shared Issue with article?

BRD9 recognizes lactate-induced H3K18 lactylation to drive oncogenic chromatin remodeling in hepatocellular carcinoma - Cell Death & Differentiation

|
By Donglei Ji, Yanjie Jia, Ze Sun, Chunfeng Gao, Caroline Zeng, Chunyu Wang, Miaomiao Yu, Linying Xie, Wenju Zhang, Yameng Li, Yingying Liang, Bai Ji, Yanzhu Yue, Yahui Liu, Ming-Ming Zhou, Lei Zeng, Enwei Wei, Guanglei Shang
| Nature Verified
Abstract Histone lactylation couples glycolytic metabolism to oncogenic transcription, but its mechanistic readers remain poorly defined. Here, we identify bromodomain-containing protein 9 (BRD9) as a lactyl-lysine reader that links lactate-driven H3K18 lactylation (H3K18la) to chromatin remodeling in hepatocellular carcinoma (HCC). Clinically, elevated H3K18la levels correlate with poor HCC prognosis.
Open in Who Shared Issue with article?
See all 12 articles