Liudmilla Rubbi

Research Paper Volume 17, Issue 3 pp 685—698 1 Computational and Systems Biology Interdepartmental Program at University of California, Los Angeles, Los Angeles, CA 90095, USA 2 Department of Molecular, Cell and Developmental Biology, University of California, Los Angeles, Los Angeles, CA 90095, USA https://doi.org/10.18632/aging.206220 How to Cite Cite this Article Select the format you require from the list below Click to copy this citation from the text box above or download the citation:...

Abstract DNA methylation is a reaction that results in the formation of 5-methylcytosine when a methyl group is added to the cytosine's C5 position. As organisms age, DNA methylation patterns change in a reproducible fashion. This phenomenon has established DNA methylation as a valuable bbiomarker in aging studies. Epigenetic clocks based on weighted combinations of methylation sites have been developed to accurately predict the age of an individual from their methylome.

Research Brief Theodore S. Nowicki, Colin Farrell, Marco Morselli, Liudmilla Rubbi, Katie M. Campbell, Mignonette H. Macabali, Beata Berent-Maoz, Begoña Comin-Anduix, Matteo Pellegrini and Antoni Ribas DOI: 10.1158/2159-8290.CD-20-0300 Published November 2020 This article requires a subscription to view the full text. You may purchase access to this article or login to access your subscription using the links below.