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Long Wen

As seen in: Wiley Online Library, arXiv, Frontiers, MDPI, ACS Publications, Canadian Journal of Infectious Diseases & Medical Microbiology, Dialnet - Universidad de La Rioja, Journal of Biomedical Optics, Journal of The American Academy of Dermatology (JAAD), International Journal of Contemporary Hospitality Management
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Articles

Advances in neurotensin receptor 1-targeted molecular probes for tumor molecular imaging and therapy

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By Jiang Fu, Shengjie Tang, Haiyang Hu, Haiyang Guo, Tao Liu, Long Wen, Yunlong Yang, Shuxuan Chen, Li Yu, Haining Zhou, Chengkuan Liu
| Frontiers
Abstract Neurotensin receptor 1 (NTS1) is a high-affinity G protein-coupled receptor (GPCR) for the endogenous peptide neurotensin (NT). NTS1 is overexpressed across multiple malignancies and is an important target for precision theranostics.
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The gastrin-releasing peptide receptor in oncology: a comprehensive review of recent advances in targeted radionuclide theranostics

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By Yunlong Yang, Jiang Fu, Sheng Jie Tang, Tao Liu, Haiyang Hu, Haiyang Guo, Long Wen, Cheng Liu, Li Yu, Haining Zhou, GuiYan Yi
| Frontiers
Abstract The gastrin-releasing peptide receptor (GRPR) is aberrantly expressed in several malignancies, including prostate cancer, breast cancer, lung cancer, and gastrointestinal stromal tumors, making it an important target for molecular imaging and targeted radionuclide therapy. In recent years, advances in radioligand design, radionuclide selection, and theranostic concepts have substantially promoted the development of GRPR-mediated oncologic applications in nuclear medicine.
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Successful Treatment of Cutaneous Squamous Cell Carcinoma Complicated by Myelodysplastic Syndrome Using Combined ALA-PDT and Narrow-Margin Excision: A Case Report

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By Zhenlin Li, Long Wen, Yunwei Yang
| Wiley Online Library Verified
For high-risk cutaneous squamous cell carcinoma (cSCC) complicated by myelodysplastic syndrome (MDS), combining narrow-margin surgical excision with 5-aminolevulinic acid photodynamic therapy (ALA-PDT) offers an effective and well-tolerated treatment option. This approach minimizes bleeding risk from thrombocytopenia while preventing recurrence in patients unsuitable for conventional wide excision or systemic therapies.
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