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Luan-Yin Chang on Muck Rack

Luan-Yin Chang

As seen in: Nature, Journal of Biomedical Science, BioRxiv, Diabetes Care Magazine
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Articles

Long-term trajectories of social adjustment and emotional/behavioral problems in pediatric post-acute COVID-19

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By Luan-Yin Chang, Susan Shur-Fen Gau, Chi-Yung Shang, Yun-Jie Tsai
| Nature Verified
Abstract COVID-19 has been associated with adverse mental health outcomes in children. However, evidence regarding the long-term trajectories of post-acute symptoms remains limited. We examined long-term emotional and behavioral trajectories in children following COVID-19 infection. Eighty-four children (aged 6–16) with a confirmed COVID-19 were initially enrolled. Of these, 69 completed the three-year follow-up assessment and were included in the present analyses.
Open in Who Shared Issue with article?

Targeting Wnt Signaling and DNAJB6/MRJ-L as a Dual Anti-RSV Strategy: Insights into a Positive Regulatory Loop

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By Chun-Yi Lu, Peng-Yeh Lai, Luan-Yin Chang, Jen-Min Huang
| BioRxiv
Abstract Respiratory syncytial virus (RSV) is a major cause of severe respiratory infections, yet effective treatments are lacking. We found that the molecular chaperon DNAJB6/MRJ plays an essential role in RSV replication. Depletion of the long isoform of MRJ (MRJ-L) suppresses RSV replication. Transcriptomic analysis revealed that MRJ-L depletion downregulates Wnt signaling pathways.
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Increased Incidence of Pediatric Type 1 Diabetes With Novel Association With Coxsackievirus A Species in Young Children but Declined Incidence in Adolescents in Taiwan

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By Wei-Liang Shih, Yi-Ching Tung, Luan-Yin Chang, Chi-Tai Fang
| Diabetes Care Magazine Verified
Epidemiology/Health Services Research Abstract OBJECTIVE Type 1 diabetes (T1D) has been linked to enterovirus infection in small population-based epidemiological studies. We investigated the secular relationship of T1D incidence with enterovirus infection and enterovirus species using nationwide population-based analysis. RESEARCH DESIGN AND METHODS We accessed the National Health Insurance Research Database of Taiwan to identify T1D and enterovirus infection cases from 2001 to 2015.
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