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Luana Girao Lessa

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Articles

Pre-existing neutralizing antibodies against cattle-transmitted influenza A virus H5N1 are detectable in unexposed individuals

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By Katharina Daniel, Leon Ullrich, Denis Ruchnewitz, Matthijs Meijers, Nico Halwe, Ursula Wild, Jan Eberhardt, Jacob Schön, Marie Wunsch, Maryna Kuryshko, Christopher R. Dietrich, Christian Kukat, Lutz Gieselmann, Henning Gruell, Donata Hoffmann, Martin Beer, Thomas C. Erren, Michael Lässig, Christoph Kreer, Florian Klein, Ricarda Stumpf, Maike Schlotz, Luana Girao Lessa, Elsayed Mohammed Abdelwhab, Andreas Pinger, Anna-Lena Schumacher, Maximilian Germer, Malena Rohde
| Cell Press Verified
Keywords influenza virus H5N1 highly pathogenic avian influenza clade 2.3.4.4b A/Texas/37/2024 humoral immunity pre-existing antibodies cross-neutralizing antibodies Introduction Sporadic human infections with highly pathogenic avian influenza A virus (HPAIV) H5N1 were first documented by spillover from birds to humans in 1997, followed by repeated outbreaks among birds with a total of 954 human cases leading to 464 deaths (48.6% case-fatality rate) between 2003 and 2024.1 In March 2024, the...
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