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Lucie Bard on Muck Rack

Lucie Bard

As seen in: BioRxiv, Cell Press
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Articles

Human neutrophils communicate remotely via glutamate-induced glutamate release

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By Olga Kopach, Lucie Bard, Piotr Michaluk, Sergyi Sylantyev
| BioRxiv
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LTP Induction Boosts Glutamate Spillover by Driving Withdrawal of Perisynaptic Astroglia

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By Christian Henneberger, Neurocentre Magendie, Lucie Bard, Aude Panatier
| Cell Press Verified
Highlights • Induction of synaptic LTP prompts withdrawal of perisynaptic astroglia • The underlying mechanisms involve NKCC1 transporter and cofilin • Reduced synaptic astroglial coverage boosts extrasynaptic glutamate escape • LTP induction thus enhances NMDAR-dependent inter-synaptic cross-talk Summary Extrasynaptic actions of glutamate are limited by high-affinity transporters expressed by perisynaptic astroglial processes (PAPs): this helps maintain point-to-point transmission in...
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