Skip To Main Content
Lusyan Dayalan on Muck Rack

Lusyan Dayalan

As seen in: BioRxiv, eLife
Is this you? As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work. Claim your profile

Get in touch with Lusyan

Contact Lusyan, search articles and posts on X, monitor coverage, and track replies from one place.

Learn more about Muck Rack

Actions

Share this page

Is this you?

As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.
Claim your profile

Articles

The insulin/IGF axis is critically important for controlling gene transcription in the podocyte

|
By Jenny A. Hurcombe, Lusyan Dayalan, Fern Barrington
| eLife
eLife Assessment This valuable study used genetic and pharmacological manipulations of insulin/IGF signaling to address the role of insulin/IGF axis in the function of renal glomerular podocyte. Solid data are presented to demonstrate that co-inhibition of insulin/IGF signaling in podocytes led to aberrant splicing of mRNAs, which could contribute to the loss of podocytes in vitro and in vivo in mice.
Open in Who Shared Issue with article?

The insulin / IGF axis is critically important controlling gene transcription in the podocyte.

|
By Jennifer A. Hurcombe, Fern Barrington, Frédéric Burdet, Lusyan Dayalan
| BioRxiv
Abstract Signalling to the podocyte via the structurally related insulin receptor (IR) or insulin-like growth factor 1 receptor (IGF1) is important for podocyte function. This study sought to elucidate the compound role of the insulin/IGF1 axis in podocytes using transgenic mice and cell culture models deficient in both receptors.
Open in Who Shared Issue with article?
See all 2 articles