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Lutiana Simoes on Muck Rack

Lutiana Simoes

As seen in: The Journal of Immunology
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Articles

Cognitive impairment, blood-brain barrier breakdown, and pro-inflammatory mediators in neonatal Escherichia coli K1 meningitis.

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By Tatiana Barichello, Jaqueline Generoso, Lutiana Simoes, Driélly Florentino, Monique Michels
| The Journal of Immunology Verified
Neonatal Escherichia coli meningitis is an important cause of mortality and morbidity in newborns. We evaluated cytokines, oxidative damage/enzymatic defense, BDNF levels, blood-brain barrier (BBB) integrity in the hippocampus of neonatal Wistar rats following E. coli K1 meningitis and subsequent behavioral parameters in adulthood. Neonatal male rats received an intracisternal injection of placebo or E. coli K1 suspension.
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