Luying Yang

"Using the right analytical tools to support developability and manufacturability studies early on is essential to ensure that the right format reaches CMC development." The structural complexity of modern ADCs, such as encompassing diverse linker–payload combinations, site‑specific conjugation strategies, and bispecific formats, demands analytical science that is both highly sophisticated and strategically deployed from the earliest stages of development.

Keywords Pediatric severe pneumonia Biomarkers CNN–BiLSTM Mortality prediction Dynamic risk assessment Get full text access Log in, subscribe or purchase for full access. References 1. de Benedictis, F.M. ∙ Kerem, E. ∙ Chang, A.B. ... Complicated pneumonia in children Lancet. 2020; 396:786-798 10253 2. Cavallazzi, R. ∙ Ramirez, J.A. Definition, Epidemiology, and Pathogenesis of Severe Community-Acquired Pneumonia Semin Respir Crit Care Med. 2024; 45(2):143-157 3. Laterre, P.F. ∙ Garber, G. ∙ Levy, H. ...

Abstract Background: For patients with poor glycemic control of adult type 1 diabetes mellitus (T1DM), in addition to managing blood glucose levels, it is worth exploring further as an early warning indicator of blood glucose control. Methods: 56 adults with T1DM, aged between 18 and 70 years, were included in the study. Data on body composition and laboratory indicators, including phase angle values and HbA1c levels, were collected.