Madline Schubert

1 Introduction Deep-fat fried products enjoy great popularity among consumers due to its characteristic and pleasant aroma and its palatability. In the last decades, the market for deep-fried products increased steadily. The global French fries market had in 2023 a volume of $16.38 billion, and it is expected that it grows up to $21.8 billion in 2028, with an annual growth rate of 5.7% [1].

Highlights • CF iPSC-derived epithelial cells are suitable for disease modeling and drug screening • Monitoring of CFTR expression during differentiation via knockin reporter cell lines • Detection of CFTR channel activity via a halide-sensitive eYFP reporter system • Conduction of a high-throughput screen for CFTR modulators using iPSC-derived cells Summary Organotypic culture systems from disease-specific induced pluripotent stem cells (iPSCs) exhibit obvious advantages compared with...