Mahvish Q. Rahim

aGVHD acute GVHD C5 complement 5 CLS capillary leak syndrome DAH diffuse alveolar hemorrhage EBMT European Society For Blood And Marrow Transplantation GVHD graft versus host disease HSCT hematopoietic stem cell transplant ICU intensive care unit IPS idiopathic pneumonia syndrome MOD multiorgan dysfunction rTA-TMA retrospectively diagnosed transplant-associated thrombotic microangiopathy TA-TMA transplant-associated thrombotic microangiopathy TBI total body irradiation VOD veno-occlusive...

CIBMTR Center for International Blood Marrow Transplant Research DF defibrotide EBMT European Blood and Marrow Transplant GVHD graft-versus-host disease HR high risk HSCT hematopoietic stem cell transplant ICU intensive care unit VHR very high risk VOD veno-occlusive disease 1 INTRODUCTION Veno-occlusive disease (VOD), also commonly referred to as sinusoidal obstruction syndrome (SOS), is a life-threatening complication that can occur after hematopoietic stem cell transplant (HSCT).

Address correspondence to: Mahvish Q. Rahim, MD, Department of Pediatrics, Riley Hospital for Children, Indiana University School of Medicine, 705 Riley Hospital Drive, ROC 4340, Indianapolis, IN 46220, USA E-mail Address: Email: E-mail Address: mqrahim@iu.edu https://orcid.org/0000-0002-3851-1979 Department of Pediatrics, Riley Hospital for Children, Indiana University School of Medicine, Indianapolis, Indiana, USA.