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Malte P. Bartram on Muck Rack

Malte P. Bartram

As seen in: Nature, The Journal of Biological Chemistry, UroToday
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Articles

Primary hyperoxaluria type 1-current practice in the siRNA era: an ERA Genes & Kidney Working Group survey.

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By Malte P. Bartram, Giovambattista Capasso, Emilie Cornec-Le Gall
| UroToday Verified
Primary hyperoxaluria type 1 (PH1) is a rare inherited metabolic disorder leading to the formation of kidney stones, nephrocalcinosis, and kidney failure. Besides, PH1 poses the risk of developing systemic oxalosis, a life-threatening condition with oxalate deposits in multiple organ systems.
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An in-depth analysis of the molecular changes induced by short-term calorie restriction before living kidney donation

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By Martin R. Späth, Sita Arjune, Katrin Bohl, Markus M. Rinschen, Christine S. Falk, Philipp Antczak, Franziska Grundmann, Torsten Kubacki, Michael Ignarski, Felix C. Koehler, Kathrin Kaufmann, Malte P. Bartram, Tristan Wagner, Michael Thomas, Adam Wahida, Christoph Schmaderer, Stephan Kemmner, Christine Kurschat, Thomas Benzing, Dirk L. Stippel, Volker Burst, Roman-Ulrich Müller, K. Johanna R. Hoyer-Allo, Jan Wilm Lackmann
| Nature Verified
Abstract Aging reduces cellular resilience and increases susceptibility to organ injury, notably acute kidney injury (AKI). Ischemia-reperfusion injury (IRI) influences outcomes after kidney transplantation. In animal models, short-term calorie restriction (CR) extends lifespan and protects kidneys from IRI, but translation to patients is limited due to incomplete mechanistic insight. This study examined clinical and molecular effects of short-term CR in living kidney donors.
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Deutsche Medizinische Wochenschrift / Abstract

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By Malte P. Bartram, Uniklinik Köln, Bodo B. Beck, Institut für Humangenetik
| thieme-connect.de
Hohe Prävalenz genetischer Nierenerkrankungen In Kohorten von Nieren-Transplantationsempfängern findet sich bei bis zu 30% eine monogene Ursache. Die Aufdeckung der genetischen Ursache von Nierenerkrankungen ist durch den technologischen Fortschritt in der DNA-Sequenzierung deutlich einfacher geworden. CKD unklarer Ätiologie Weiterhin können nicht alle Fälle aufgeklärt werden.
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