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Manuel Bita Ongolo on Muck Rack

Manuel Bita Ongolo

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Articles

Heart failure-induced reprogramming of salt-evoked neurovascular coupling in the rat hypothalamus

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By Ranjan Roy, Jessica A. Filosa, Manuel Bita Ongolo
| Wiley Online Library Verified
Introduction Neurovascular coupling (NVC) is a well-established phenomenon in the brain that involves a tight coupling between neuronal activity and increased cerebral blood flow (CBF) (Iadecola, 2017; Urban et al., 2017). This activity-dependent increase in CBF (also known as functional hyperaemia) occurs rapidly (<2 s) and in a spatially restricted manner (Li et al., 2009; Silva et al., 2000), ensuring the optimal delivery of glucose and oxygen to brain areas with increased metabolic demand.
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