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As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.Articles
A Prostatic Intraepithelial Neoplasia-Dependent p27Kip1 Checkpoint Induces Senescence and Inhibits Cell Proliferation and Cancer Progression
(Cancer Cell 14, 146–155; August 12, 2008) This publication showed that the induction of p27Kip1 and senescence in luminal epithelial cells of prostatic intraepithelial neoplasia inhibits progression to invasive prostate cancer through a mouse model. We, the editors of Cancer Cell, were informed in January 2024 about inconsistencies in Figure 7C, where separate immunoblot images were merged and represented as if derived from the same blot.
Dysregulation of the PRUNE2/PCA3 genetic axis in human prostate cancer: from experimental discovery to validation in two independent patient cohorts
Background: We have previously shown that the long non-coding (lnc)RNA prostate cancer associated 3 (PCA3; formerly prostate cancer antigen 3) functions as a trans-dominant negative oncogene by targeting the previously unrecognized prostate cancer suppressor gene PRUNE2 (a homolog of the Drosophila prune gene), thereby forming a functional unit within a unique allelic locus in human cells.
TRAGIC INDIFFERENCE: One Man's Battle with the Auto Industry over the Danger of SUVs
Adam L. Penenberg, . . Harper Business, $25.95 (352pp) ISBN 978-0-06-009058-6 In a stinging invective, journalist Penenberg outlines the ethical failures and calculated improprieties of two principal automotive-industry companies, along with the struggle of attorney Tab Turner to hold them accountable.
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