Marc E. Buyse on Muck Rack

Marc E. Buyse

San Francisco
As seen in: Memory Studies, BMJ Open, Cancer Investigation, JAMA Oncology, The New England Journal of Medicine, EClinicalMedicine, The Lancet, Journal of Clinical Oncology, Future Medicine, European Urology and
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Articles

Regional variation in clinical-trial risks: a large-scale analysis of 585 clinical trials

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By Sylviane de Viron, Steve Young, Laura Trotta, Marc E. Buyse
| BMJ Open
STRENGTHS AND LIMITATIONS OF THIS STUDY The analysis used a large dataset covering 585 trials and more than 56 000 sites. Sites were grouped into predefined geographic regions to enable cross-region comparison. Key Risk Indicators (KRIs) were selected because they are standardised and widely used across trials. Heterogeneity was assessed using forest plots of relative KRI risk scores by phase, study size, therapeutic area and region.
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Use of surrogate endpoints in health technology assessment and reimbursement of treatments for the management of chronic kidney disease

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By Rod S. Taylor, Marc E. Buyse, Louvain La Neuve, SDA Bocconi
| EClinicalMedicine
Keywords Surrogate outcomes Health technology assessment Reimbursement Chronic kidney disease Search strategy and selection criteria Data for this review were based on a previous scoping literature review of the use of surrogate endpoints in clinical trials and health policy that undertook searches of a number of bibliographic databases (EMBASE, MEDLINE, Cochrane Methodology Register) using search terms including “surrogate end points”, “guidelines”, and “trials” for articles published in...
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Use of surrogate endpoints in health technology assessment and reimbursement of treatments for the management of chronic kidney disease

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By Rod S. Taylor, Marc E. Buyse, Louvain La Neuve, SDA Bocconi
| EClinicalMedicine
ReviewVolume 88103465Open access aRobertson Centre for Biostatistics & General Practice and Primary Care, School of Health and Wellbeing, University of Glasgow, Glasgow, UK bDepartment Clinical Pharmacy and Pharmacology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands cInternational Drug Development Institute (IDD), Biostatistics, Louvain la Neuve and University of Hasselt, I-BioStat, Hasselt, Belgium dCenter for Research on Health and Social Care...
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