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Articles by Marcus Ang
A clinical multimodal vision language foundation model with fine-grain explainability
3 hours ago Nvidia CEO Jensen Huang names Germany, Japan and China as the world’s leading countries in manufacturing and advanced technology, explaining how computing and digitalisation reshaped global industry. Nvidia CEO Jensen Huang has identified Germany, Japan and China as the three countries at the …
A clinical multimodal vision language foundation model with fine-grain explainability
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Abstract Despite their considerable promise, many current medical foundation models remain modality specific and lack transparent reasoning, limiting clinical adoption. To address this gap, we introduce Explainable Vision Language Foundation Model for Medicine (EVLF-FM), a multimodal vision language foundation model that combines broad diagnostic capabilities with fine-grained explainability.
By Yang Bai, Haoran Cheng, Yang Zhou, Jun Hao Zhou, Arun J. Thirunavukarasu, Yuhe Ke, Jie Yao, Kanae Fukutsu, Laura Gutierrez, Laura Gutiérrez, Alessandro Berni, Zhen Ling Teo, Brian T. Soetikno, Christopher Nielsen, Tobias Elze, Zengxiang Li, Sumit Sharma, Nicholas Ruthmann, Le Linh, Hiok Hong Chan, Victor Koh, Marcus Tan, Kelvin Li, Leonard W Yip, Yih Chung Tham, Leopold Schmetterer, Rae-Young Kim, Damon Wong, Marcus Ang, Rahat Hussain, Jodhbir S Mehta, Tin Aung, Lionel Tim-Ee Cheng, Darius M. Moshfeghi, Nan Liu, Iain Beehuat Tan, Eyal Klang, Yong Liu
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Nature
Verified
Global Axial Length Centile Charts
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By Sander Kneepkens, Gareth Lingham, James Loughman, Niall C Strang, Yih Chung Tham, Síofra Harrington, Laura Guisasola, Amanda French, Xiangui He, David Mackey, Rigmor C. Baraas, Olavi Pärssinen, Jason C. Yam, Kathryn Saunders, Jeremy Guggenheim, Seang Mei Saw, Weizhong Lan, Caroline C. W. Klaver, D. Ian Flitcroft, Fabian SL Yii, Sara J. McCullough, Ellen Svarverud, Trine Langaas, Cathy Williams, Cécile Delcourt, Christopher Hammond, Peilun Dai, Daniel K. Ting, Katie Williams, Klaus Nordhausen, Jun Chen, Xun Xu, Li Yong, Marcus Ang, Micheal Moore, Wei Pan, Samantha Lee, Virginie J. M. Verhoeven, Wu Fan, Yuzhou Zhang, Jun L Zhou, Mariam El Gharbi, Alba Galdón, Jani Moilanen, Wan-Ting Loke, Tina R. Johansen, Gro Horgen, Dirk J. van Hemert, Lene A. Hagen, CREAM-Kids Consortium, Marja-Liisa Franssila, Niko Setälä, Joan Pérez-Corral, Hanne-Mari S. Thorud, Cecilie O. Bjørset, Hilde R. Pedersen, Stuart J. Gilson
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JAMA Network
Verified
Github Copilot helped us cut down 50-75% time in our e-commerce business
This is a submission for the GitHub Finish-Up-A-Thon Challenge What I Built A couple of years ago, I went back home after a decade of being a full-fledged web developer and started helping out in a family business. Of course, obviously I had to learn the ropes from the production floor up till office work, since it is an e-commerce centric business. Then I noticed something, we are manually writing down SKU codes on each waybill.
How AI Can Help to Manage Juvenile-Onset Myopia
July 1, 2025 By Marcus Ang, MBBS, MMED, MCI, FRCS, PhD The incidence of juvenile-onset myopia is rising.
Anterior Segment Optical Coherence Tomography Angiography: A Review of Applications for the Cornea and Ocular Surface
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Challenges in Assessing Dose-Dependent Atropine for Myopia-Reply
Challenges in Assessing Dose-Dependent Atropine for Myopia—Reply Topical Atropine for Childhood Myopia Control Yong Li, MD; Michelle Yip, MD; Yilin Ning, PhD; Joey Chung, BSc; Angeline Toh, BA; Cheryl Leow, BSc; Nan Liu, PhD; Daniel Ting, MD, PhD; Leopold Schmetterer, PhD; Seang-Mei Saw, PhD; Jost B. Jonas, MD; Audrey Chia, PhD; Marcus Ang, PhD Challenges in Assessing Dose-Dependent Atropine for Myopia Jan-Roelof Polling, PhD; Caroline C. W.
Anterior Segment Optical Coherence Tomography Angiography: A Review of Applications for the Cornea and Ocular Surface
Preprint Review Version 1 This version is not peer-reviewed Version 1 : Received: 23 August 2024 / Approved: 23 August 2024 / Online: 26 August 2024 (11:08:09 CEST) Lee, B. J. H.; Tey, K. Y.; Cheong, E. Z. K.; Wong, Q. Y.; Chua, S. Q.; Ang, M. Anterior Segment Optical Coherence Tomography Angiography: A Review of Applications for the Cornea and Ocular Surface. Preprints 2024, 2024081744. https://doi.org/10.20944/preprints202408.1744.v1 Lee, B. J. H.; Tey, K. Y.; Cheong, E. Z. K.; Wong, Q. Y.; Chua, S.
Comparative Study of Primary SMILE, SMILE Enhancement, and Femtosecond Laser–Assisted LASIK on Higher Order Aberrations and Corneal Densitometry | Journal of Refractive Surgery
The authors thank Ms. Sasha Ang for her contributions to the data collection and organization. Correspondence: Jodhbir S. Mehta, FRCOphth, FRCS(Ed), PhD, Singapore National Eye Centre, Cornea and Refractive Services, 11 Third Hospital Avenue, Singapore, 168751, Singapore.
Jan. 19: 2nd Annual Global YO Summit in Singapore
Young ophthalmologist engagement around the world has grown by leaps and bounds. In the Asia Pacific region alone, for example, Singapore was the only place where a formal YO Society existed in 2016. Today we can count nearly 20 YO committees and societies in the region. That is one reason a full day has been set aside for YOs at the in Singapore on Friday, Jan. 19, 2024. It will be held along with the 37th Singapore-Malaysia Joint Ophthalmic Conference from Jan. 19 to 21.
Predictors of myopic macular degeneration in a 12-year longitudinal study of Singapore adults with myopia
Abstract Purpose To investigate the predictive factors for myopic macular degeneration (MMD) and progression in adults with myopia. Methods We examined 828 Malay and Indian adults (1579 myopic eyes) with myopia (spherical equivalent (SE) ≤–0.5 dioptres) at baseline who participated in both baseline and 12-year follow-up visits of the Singapore Malay Eye Study and the Singapore Indian Eye Study. Eye examinations, including subjective refraction and axial length (AL) measurements, were performed.
Artificial intelligence and digital health in global eye health: opportunities and challenges
Introduction Global eye health is defined by The Lancet Global Health Commission as the degree to which vision, ocular health, and function are maximised worldwide, thereby optimising overall wellbeing and quality of life.1 In addition to being a substantial source of morbidity around the world, vision impairment also has an important influence on economic productivity, with an estimated global productivity loss from visual impairment amounting to US$410·7 billion in 2020.2 Improvements in...
Multi-task learning approach for volumetric segmentation and reconstruction in 3D OCT images
K. Devarajan, R. Sim, J. Chua, C. W. Gong, S. Matsumura, H. M. Htoon, L. Schmetterer, S. M. Saw, and M. Ang, “Optical coherence tomography angiography for the assessment of choroidal vasculature in high myopia,” Br. J. Ophthalmol. 104(7), 917–923 (2020). [Crossref] A. P. Yow, R. Srivastava, J. Cheng, A. Li, J. Liu, L. Schmetterer, H.L. Tey, and D. W. K. Wong, “Techniques and applications in skin OCT analysis,” Adv. Exp. Med. Biol. 1213, 149–163 (2020).. PMID: 32030669. [Crossref] A. A. Novikov, D. Major, M. Wimmer, D.
Retinal photograph-based deep learning algorithms for myopia and a blockchain platform to facilitate artificial intelligence medical research: a retrospective multicohort study
Introduction Myopia is a substantial global health challenge.1,2 The number of individuals with myopia is projected to reach almost 5 billion by 2050, of whom 20% will have high myopia.2,3 This global burden is unevenly distributed, with substantially higher rates of myopia in east Asia.2 Visual impairment can be reversed with optical correction (eg, spectacles) in more than 90% of people with low or moderate levels of myopia.4,5 However, patients with high myopia have the potential risk of...
ScienceTalk: Don't be short-sighted about myopia in children
SINGAPORE - Myopia, or near-sightedness, makes objects at a distance out of focus. While spectacles or contact lenses correct this easily, many people do not realise that developing myopia leads to irreversible changes to our eyes, such as excessive eyeball elongation.
Refractive surgery beyond 2020
Abstract Refractive surgery refers to any procedure that corrects or minimizes refractive errors. Today, refractive surgery has evolved beyond the traditional laser refractive surgery, embodied by the popular laser in situ keratomileusis or ‘LASIK’. New keratorefractive techniques such as small incision lenticule extraction (SMILE) avoids corneal flap creation and uses a single laser device, while advances in surface ablation techniques have seen a resurgence in its popularity.
SARS-CoV-2 infection in conjunctival tissue
In a recent study published in The Lancet Respiratory Medicine in May, 2020, Kenrie Hui and colleagues 1 Hui KPY Cheung M-C Perera RAPM et al. Tropism, replication competence, and innate immune responses of the coronavirus SARS-CoV-2 in human respiratory tract and conjunctiva: an analysis in ex-vivo and in-vitro cultures. Lancet Respir Med.
Randomized Clinical Trial Comparing Femtosecond LASIK and Small-Incision Lenticule Extraction
Purpose To compare femtosecond LASIK with small-incision lenticule extraction (SMILE) for the treatment of myopia and myopic astigmatism. Design Prospective, randomized, paired-eye, single-masked clinical trial. Participants Consecutive eligible patients were randomized to undergo SMILE and LASIK in either eye at a single tertiary referral eye center. Methods Patients were treated in each eye using the VisuMax (Carl Zeiss Meditec, Jena, Germany) 500-kHz femtosecond laser system.
Functional Optical Zone and Centration Following SMILE and LASIK: A Prospective, Randomized, Contralateral Eye Study
PURPOSE: To compare centration and functional optical zone (FOZ) after small incision lenticule extraction (SMILE) and femtosecond laser–assisted in situ keratomileusis (LASIK). METHODS: In this prospective, randomized, single-masked, paired-eyed, clinical trial, 70 patients received SMILE in one eye and LASIK in the other eye for myopia and myopic astigmatism.
Intraoperative Patient Experience and Postoperative Visual Quality After SMILE and LASIK in a Randomized, Paired-Eye, Controlled Study
Fear and anxiety may affect patient cooperation during surgery, with increased risk of complications in uncooperative or fearful patients.1 Therefore, it is of great value to evaluate the patient intraoperative experience to improve preoperative patient counselling. Detailed information of what to expect during surgery may help to reduce patient anxiety and thereby reduce the risk of intraoperative complications.
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