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Mariangela Sociale

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Articles

Ceramide Synthase Schlank Is a Transcriptional Regulator Adapting Gene Expression to Energy Requirements

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By Mariangela Sociale, Anna-Lena Wulf, Bernadette Breiden, Lipid Biochemistry
| Cell Press Verified
Mutation of the NLS2 Motif Impairs DNA Binding and Thereby Transcriptional Regulation Our results provide a molecular mechanism by which the enzyme CerS Schlank, a multiple TM protein, for which we previously identified a nuclear pool at the INM (Voelzmann et al., 2016xNuclear Drosophila CerS Schlank regulates lipid homeostasis via the homeodomain, independent of the lag1p motif.
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