Mariel Vazquez
Davis, San Francisco
Prof @ucdavis. Scientist, Advocate, mathematician, DNA topology, art and music lover. Working towards a better world for everyone. Tweets mine. She/her.
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Articles by Mariel Vazquez
Analyzing the link between RNA secondary structures and R-loop formation with tree polynomials
Abstract R-loops are a class of non-canonical nucleic acid structures that typically form during transcription, when the nascent RNA hybridizes with the DNA template strand, leaving the DNA coding strand unpaired. Co-transcriptional R-loops are abundant in nature and biologically relevant. Recent research shows that DNA sequence and topology affect R-loops, and yet it remains unclear how these and other factors drive R-loop formation.
Math shows how DNA twists, turns and unzips
If you’ve ever seen a picture of a DNA molecule, you probably saw it in its famous B-form: two strands coiling around each other in a right-handed fashion to form a double helix. But did you know that DNA can change its shape? DNA molecules, which carry the genetic code of an organism, have to be tightly packed to fit inside a cell. However, every few hours, the cell produces a faithful copy of its genome in preparation for cell division.
Math shows how DNA twists, turns and unzips
DNA molecules, which carry the genetic code of an organism, have to be tightly packed to fit inside a cell. However, every few hours, the cell produces a faithful copy of its genome in preparation for cell division. This replication process puts tremendous stress on the DNA and can change its shape in lethal ways. As a mathematician and a biologist, I am interested in how mathematics can describe the many shapes of DNA, as well as cellular processes like DNA replication.
Math shows how DNA twists, turns and unzips
(The Conversation is an independent and nonprofit source of news, analysis and commentary from academic experts.)(THE CONVERSATION) If you’ve ever seen a picture of a DNA molecule, you probably saw it in its famous B-form: two strands coiling around each other in a right-handed fashion to form a double helix. But did you know that DNA can change its shape?DNA molecules, which carry the genetic code of an organism, have to be tightly packed to fit inside a cell.
Math shows how DNA twists, turns and unzips
(The Conversation is an independent and nonprofit source of news, analysis and commentary from academic experts.)(THE CONVERSATION) If you’ve ever seen a picture of a DNA molecule, you probably saw it in its famous B-form: two strands coiling around each other in a right-handed fashion to form a double helix. But did you know that DNA can change its shape? DNA molecules, which carry the genetic code of an organism, have to be tightly packed to fit inside a cell.
Math shows how DNA twists, turns and unzips
If you’ve ever seen a picture of a DNA molecule, you probably saw it in its famous B-form: two strands coiling around each other in a right-handed fashion to form a double helix. But did you know that DNA can change its shape? DNA molecules, which carry the genetic code of an organism, have to be tightly packed to fit inside a cell. However, every few hours, the cell produces a faithful copy of its genome in preparation for cell division.
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