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Microwave‐Enhanced Synthesis of 2‐Styrylquinoline‐4‐Carboxamides With Promising Anti‐Lymphoma Activity
1 Introduction Non-Hodgkin lymphoma (NHL) represents an extremely heterogeneous group of lymphoid cancers arising from the malignant transformation of B and T lymphocytes, and, less frequently, natural killer (NK) cells. A wide array of subtypes exists, distinguished by unique molecular, cellular, and immunological features impacting their pathogenesis, clinical presentation, and treatment response [1, 2].
IJMS | Free Full-Text | HSV-1 Glycoprotein D and Its Surface Receptors: Evaluation of Protein-Protein Interaction and Targeting by Triazole-Based Compounds through In Silico Approaches
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GPCR Inhibition in Treating Lymphoma
G protein-coupled receptors (GPCRs) are the largest family of integral membrane proteins in the human genome and mediate the majority of cellular responses to endogenous (amines, cations, lipids, peptides and glycoproteins) and exogenous (therapeutic drugs, light, tastants, and odorants) ligands and stimuli.
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