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Late-life semaglutide treatment slows ageing and extends lifespan in female mice
Abstract Pharmacological glucagon-like peptide-1 receptor (GLP-1R) activation reduces food intake and is an effective therapy for type 2 diabetes and obesity1. The use of GLP-1 medicines has revealed pleiotropic beneficial effects beyond glucose and weight control2,3,4,5, but little is known about the underlying basis of the pleiotropic effects.
Author Correction: Trained immunity links hematopoietic stem cell aging to aging-associated inflammation
Correction to: Nature Aging https://doi.org/10.1038/s43587-026-01175-2, published online 16 July 2026. In the version of this article initially published, the name of K. Claire Tsuei was listed incorrectly (Clair Tsui) and is now amended in the HTML and PDF versions of the article.
SIRT2 and NAD+ Boosting Broadly Suppress Aging‐Associated Inflammation
1 Introduction Aging is a complex process that induces changes at the molecular, cellular, and organismal levels, ultimately contributing to the onset of aging-related conditions and diseases. One hallmark of aging is chronic low-grade inflammation, commonly referred to as “inflammaging” (López-Otín et al. 2023). Several immune pathways have been shown to be activated during aging, contributing to aging-associated inflammation.
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