Mário Barros
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From Yeast to Therapeutics: Modeling Neurodegenerative Diseases in Saccharomyces cerevisiae
1 Introduction Saccharomyces cerevisiae serves as a powerful model for studying neurodegenerative diseases. Although it is impossible to study all the different aspects underlying neurodegenerative diseases in unicellular organisms, factors that cause protein pathologies can be studied in yeast.
Saccharomyces cerevisiae Dmo2p is required for the stability and maturation of newly translated Cox2p
Conflict of interest The authors declare no conflict of interest. Supporting Information Filename Description febs70009-sup-0001-FigsS1-S8.docxWord 2007 document , 1.8 MB Fig. S1. DMO2 proteomics from y3kproject.org website. Fig. S2. Global genetic interaction of dmo2Δ mutant obtained from thecellmap.org website. Fig. S3. Serial dilution test in rich fermentable glucose medium (YPD) and rich non-fermentable ethanol-glycerol medium (EG). Fig. S4. Dmo2p sequence alignments and modeling. Fig. S5.
Designing with words: exploring the integration of text-to-image models in industrial design
ABSTRACT This study investigates the effectiveness of Text-to-image (T2I) models in assisting industrial designers with the visualization of product concepts. Using action research and a reflection-in-action, this research conducts a series of experiments utilizing Stable Diffusion for generating chair concepts.
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