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Mario Pende

As seen in: Nature, Cell Press
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Articles by Mario Pende

The integrated stress response promotes immune evasion through lipocalin 2 - Nature

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By Jozef P. Bossowski, Ray Pillai, John Kilian, Angela Lau, Mari N Nakamura, Ali Rashidfarrokhi, Yuan Hao, Ruxuan Li, Katherine P. Wu, Takamitsu Hattori, Eliezra Glasser, Akiko Koide, Lidong Wang, André Moreira, Cristina H Hajdu, Sahith Rajalingam, Sarah LeBoeuf Verified, Hortense Le, Seungeun Thera Lee, Cheolyong Joe, Hyemin Kim, Chan-Young Ock, Se-Hoon Lee, Hao Wang, Volkan I. Sayin, Aristotelis Tsirigos, Kwok-Kin Wong, Sergei B Koralov, Mario Pende, Francisco J. Sanchez-Rivera, Diane Simeone, Ioannis K. Zervantonakis, Shohei Koide, Thales Papagiannakopoulos, Angana A. H. Patel
| Nature Verified
Abstract Cancer cells activate the integrated stress response (ISR) to adapt to stress and resist therapy1. ISR signals converge on activating transcription factor 4 (ATF4), which controls cell-intrinsic transcriptional programs that are involved in metabolic adaptation, survival and growth2,3. However, whether the ISR–ATF4 axis influences anti-tumour immune responses remains mostly unknown.
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Nutrient-regulated control of lysosome function by signaling lipid conversion

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By Michael Ebner, Dmytro Puchkov, Orestes López-Ortega, Pathma Muthukottiappan, Yanwei Su, Christopher Schmied, Gillian L. Dornan, Max T. Lucht, Wonyul Jang, Philipp Koch, Alexander Wallroth, Martin Lehmann, Britta Brügger, Mario Pende, Dominic Winter, Volker Haucke, Silke Zillmann, Iryna Nikonenko, Jochen Koddebusch, Vonda Koka
| Cell Press Verified
Main text (Cell 186, 5328–5346.e1–e12; November 22, 2023) In the originally published version of this article, we noted two errors: Figure S2D erroneously showed the same graph as in Figure 1C. The error was introduced by the authors when replacing the low-resolution graphs used during the review process with high-resolution editable versions for final publication.
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Golgi mechanics controls lipid metabolism

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By Manuel Théry, Mario Pende, Universite Grenoble-Alpes, Université Paris Diderot
| Nature Verified
Cell metabolism ensures that cell dynamics and continued renewal are supported by a constant flow of matter that consumes energy. A new study shows that cell metabolism is sensitive to mechanical cues, revealing that the level of cell contraction modulates the production and storage of lipids, which could serve as fuel for energy production. Access optionsAccess options Subscribe to Journal Get full journal access for 1 year $225.00 only $18.75 per issue All prices are NET prices.
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By Hendrik Nolte, Manuela Marabita, Martina Baraldo, Francesca Solagna, Roberta Sartori, Ivan Nemazanyy, Stéphane Pyronnet, Marcus Kruger, Mario Pende, Bert Blaauw
| secure.jbs.elsevierhealth.com
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