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Mark Dowling on Muck Rack

Mark Dowling

Verified
Cheshire
As seen in: Chester & District Standard's, Illumination, Medium, Nature, The Daily Mirror, Science Magazine, Scottish Daily Record, Cell Press, Bournemouth Daily Echo, The Argus, Lancashire Telegraph and
News desk journalist for the Chester Standard. Tweets about Chester news, Chester FC and other, distinctly non-Chester-related, stuff.
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Articles

Pre-transplant azacitidine does not improve survival in allogeneic HSCT for higher-risk MDS

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By Miles B. Horton, Becky Leung, Ricky Nelles, Mark Dowling Verified, Stewart Hunt, Lynette Chee, Ashleigh Scott, David Ritchie, Devendra Hiwase, Duncan Purtill, Glen Kennedy, Ashish Bajel, Matthew Rubic, Christopher McKinnely, Alia Cibich, Abir Bhattacharya
| Nature Verified
To the Editor: Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is the only curative therapy for myelodysplastic syndromes (MDS) and optimising patients for transplant is critical to achieving the best outcomes [1, 2]. Hypomethylating agents (HMAs), particularly azacitidine, are used as a bridging strategy with the aim of achieving disease control and limiting leukemic transformation.
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Long-lived IgE plasma cells persist in secondary lymphoid tissues using a navitoclax-sensitive survival program

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By Zhoujie Ding, Mark Dowling Verified, Adam K. Wade-Vallance, Alexandra R. Dvorscek, Catherine Pitt, Jesse D. Mulder, Kristy O’Donnell, Craig I. McKenzie, Craig Mckenzie, Olaf Perdijk, Danika L. Hill, Isaak Quast, David Tarlinton, Christopher Allen, Marcus Robinson, Alexandra Bosak Karaviotis, Julia Scrofani
| Cell Press Verified
Keywords IgE allergy antibody-secreting cell plasma cell plasmablast MCL1 BCL2 BCLXL ABT-263 apoptosis Introduction Immunoglobulin E (IgE) antibody is a critical mediator of allergic diseases, binding mast cells and basophils to elicit their degranulation upon exposure to allergen, triggering allergy symptoms.1 Although serum IgE can persist for months in the absence of known allergen exposure,2,3 the lifespan of IgE antibody-secreting cells (ASCs) is unclear.
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Cash Flow Isn’t Glamorous

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By Mark Dowling Verified
| Medium
Published Weekly: Smart And Simple Tweaks That Bulletproof Your Business And Confound Your Competition. Small Business. Made Simple. Follow publication But hey, it keeps the door open… Money talks, but cash flow sings. Trust me on this, if nothing else. Because it’s something I’ve seen more than once. In their pursuit of growth metrics, most (thankfully, not all) business owners I’ve worked with overlook the fundamental rhythm of business survival.
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