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Baseline Gut Microbiome Profiling in Therapy-Naive Patients with Locally Advanced Rectal Cancer Identifies Signatures of Response to Total Neoadjuvant Therapy
Background/Objectives: Total neoadjuvant therapy (TNT) is standard for locally advanced rectal cancer, yet treatment response is biologically heterogeneous, underscoring the need for predictive biomarkers. This study aimed to characterize how baseline and on-treatment gut microbiome ecology relate to clinically relevant response dimensions, and to identify baseline-level markers that could be integrated into a pre-treatment response score.
Diagnostics | Free Full-Text | Recurrence Patterns after Radiotherapy for Glioblastoma with [(11)C]methionine Positron Emission Tomography-Guided Irradiation for Target Volume Optimization
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
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