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Maryem A. Hussein on Muck Rack

Maryem A. Hussein

As seen in: HAL, The Journal of Biological Chemistry
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Articles

LXR-Mediated ABCA1 Expression and Function Are Modulated by High Glucose and PRMT2

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By Maryem A. Hussein, Elina Shrestha, Mireille Ouimet, Tessa J. Barrett
| HAL
Article Dans Une Revue PLoS ONE Année : 2015 LXR-Mediated ABCA1 Expression and Function Are Modulated by High Glucose and PRMT2 Fichier principal LXR-Mediated ABCA1 Expression and.pdf (909) Télécharger le fichier Origine Publication financée par une institution Licence hal-04963127 , version 1 (24-02-2025) Maryem A. Hussein, Elina Shrestha, Mireille Ouimet, Tessa J. Barrett, Sarah Leone, et al.. LXR-Mediated ABCA1 Expression and Function Are Modulated by High Glucose and PRMT2.
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Poly(ADP-ribose) Polymerase 1 Represses Liver X Receptor-mediated ABCA1 Expression and Cholesterol Efflux in Macrophages

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By Mireille Ouimet, Elina Shrestha, Maryem A. Hussein, Jeffery N. Savas, Tessa J. Barrett
| The Journal of Biological Chemistry Verified
Liver X receptors (LXR) are oxysterol-activated nuclear receptors that play a central role in reverse cholesterol transport through up-regulation of ATP-binding cassette transporters (ABCA1 and ABCG1) that mediate cellular cholesterol efflux. Mouse models of atherosclerosis exhibit reduced atherosclerosis and enhanced regression of established plaques upon LXR activation. However, the coregulatory factors that affect LXR-dependent gene activation in macrophages remain to be elucidated.
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