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Matthew Brian Dodson on Muck Rack

Matthew Brian Dodson

As seen in: Nature, PLOS Biology, MDPI, Science Magazine, Cell Chemical Biology, Cell Press, RC Car Action, Pagosa Springs Sun
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Articles

The pyrimidinosome is cancer's Achilles' heel

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By Matthew Brian Dodson, Donna D. Zhang, Zhang DD
| ncbi.nlm.nih.gov
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The pyrimidinosome is cancer’s Achilles’ heel - Nature Cell Biology

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By Matthew Brian Dodson, Donna D. Zhang
| Nature Verified
A new study shows that the enzymes involved in de novo pyrimidine synthesis and ferroptosis form a complex called the pyrimidinosome, which is controlled by AMPK. Cancer cells low in AMPK expression rely on the pyrimidinosome, suggesting that co-inhibition of AMPK and the pyrimidinosome represents a potential cancer treatment strategy. De novo pyrimidine synthesis is a vital process for cell proliferation.
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Arsenic in Drinking Water and Diabetes

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By Aryatara Shakya, Matthew Brian Dodson, Mónica D Ramírez-Andreotta, Janick F. Artiola
| MDPI
Abstract : Arsenic is ubiquitous in soil and water environments and is consistently at the top of the Agency for Toxic Substances Disease Registry (ATSDR) substance priority list. It has been shown to induce toxicity even at low levels of exposure. One of the major routes of exposure to arsenic is through drinking water.
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