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Mattieu Zhai on Muck Rack

Mattieu Zhai

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Articles

Premature senescence impairs hematopoietic stem cell function during sickle cell disease in mice and humans

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By Emily Hendrix, Heather Lin Verified, Aditya Barve, Preeti Dabas, Adam Cornwell, Pramika Sriram, Alex Kopyov, Emilia Kooienga, James Johnson, Jacquelyn Myers, Esther A. Obeng, Guolian Kang, Yunusa Olufadi, Terri L Cain, Lindsay Talbot Verified, Mauricio Cortes, Samuel Miller, Dirk Loeffler, AKSHAY SHARMA, Shannon McKinney-Freeman, Mattieu Zhai, Zakiya Kelley
| Science Magazine Verified
Editor’s summary Abstract Supplementary Materials REFERENCES AND NOTES Information & Authors Metrics & Citations Check Access References Figures Tables Media Share Editor’s summary Sickle cell disease (SCD) causes hematopoietic stem and progenitor cell (HSPC) dysfunction and is associated with increased risk of myeloid malignancies, also possibly selecting for mutant hematopoietic clones, although the underlying pathophysiology is not fully understood.
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