Yunusa Olufadi

Conflicts of Interest The authors declare no conflicts of interest. Andrew M. Heitzer and Jane S. Hankins receive consultancy fees from Global Blood Therapeutics. Supporting Information Filename Description pbc31531-sup-0001-SuppMat.docx54.9 KB Supporting Information References 1, , , et al., “Obstructive Sleep Apnea and Sickle Cell Anemia,” Pediatrics 134, no. 2 (2014): 273–281. 2, , and , “Hemoglobinopathies and Sleep—The Road Less Traveled,” Sleep Medicine Reviews 24 (2015): 57–70.

Results CDCAI visit 1 (2010–2013) had 86% successful recruitment,21 with N = 817 available for analysis and follow-up. The time between visit 1 and visit 2 (2017–2019) ranged from 3.8 to 9.1 years, with a mean 6.7 (SD: 1.1). Of the 817 who participated in visit 1, 71 (8.7%) were not available or lost to follow-up and 232 (28.4%) died before they could enroll and/or complete study activities, leaving 515 successfully invited to participate in the follow-up visit 2 examination.