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Max Duarte

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Articles

The ribonucleoprotein-mediated CRISPR‒Cas9 system induces recurrent Aire gene mutations in contrast to the nickase expression vector in murine in vitro or in vivo models

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By Pedro Tanaka, Max Duarte, Cintia J Monteiro, Ernna H Oliveira
| BioRxiv
Abstract Although in vitro mTEC cultures can help determine the role of the autoimmune regulator (Aire) gene, the mechanisms of Aire mutations were identified using Aire mutant mice. Nevertheless, long-term cultures of mTECs from mice are difficult to establish. To overcome this, we used a CRISPR‒Cas9 system to edit Aire in a murine mTEC line in vitro and mouse embryos. Two ribonucleoprotein (RNP) complexes were designed to separately target Aire exons 6 and 8.
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Looney Tunes Mayhem Review - Surprisingly Tactical Chaos

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By Matthew Aguilar Verified, Alexio Schneeberger, Max Duarte
| ComicBook Verified
CMON is embracing the chaotic fun of the Looney Tunes franchise with their brand new board game Looney Tunes Mayhem, and those who jump in will find the franchise's trademark humor and zaniness intact. The game features lovable characters like Bugs Bunny, Tweety Bird, and Wile E. Coyote, and players will create a team of two to take on their opponent in an attempt to gain 5 Victory Points.
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