Mayté Castro Jimenez

Abstract Parkinson’s disease leads to a spectrum of locomotor deficits that vary in severity with the nature of daily activities and the fluctuating physiology of patients. Many of these deficits remain inadequately addressed by existing deep brain stimulation therapies that rely on activity-agnostic parameters optimized for cardinal motor symptoms. By contrast, therapies embedding activity-specific parameters have the potential to better address the entire range of symptoms.

Ayuda Buscar en la ayuda Buscar en la ayuda Cisternografía radioisotópica con 99Tc-DTPA para confirmación diagnóstica de la hidrocefalia oculta normotensa Roberto León Castellón [1] ; Mayté Castro Jiménez [2] ; Irma Regla Olivera Leal [2] ; Juan Miguel Martín Escuela [2] ; Silvia Salva Camaño [2] ; Adlín López Díaz [2] ; Léster Rodríguez Paleo [2] ; Aley Palau San Pedro [2] [1] Hospital Universitario General Calixto García [2] Hospital Clínico Quirúrgico Hermanos Ameijeiras Localización:...

Abstract People with late-stage Parkinson’s disease (PD) often suffer from debilitating locomotor deficits that are resistant to currently available therapies. To alleviate these deficits, we developed a neuroprosthesis operating in closed loop that targets the dorsal root entry zones innervating lumbosacral segments to reproduce the natural spatiotemporal activation of the lumbosacral spinal cord during walking.