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Meggy Suarez-Carmona on Muck Rack

Meggy Suarez-Carmona

As seen in: Color Research & Application, Nature
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Articles

Harnessing lipid-driven immunometabolic pathways in omental metastases to enhance immunotherapy in patients with ovarian cancer - Signal Transduction and Targeted Therapy

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By Meggy Suarez-Carmona, Mareike Hampel, Xin-Wen Zhang, Nektarios A. Valous, Pornpimol Charoentong, Dyke Ferber, Jannis Wissfeld, Stanislas Goriely, Abdulkader Azouz, Anthony Rongvaux, Sven Zukunft, Ingrid Fleming, Jürgen G. Okun, Vickie E. Baracos, Mathias Heikenwalder, Laurence Zitvogel, Xinyi Xu, Chenqi Xu, Michael Volkmar, Daniel Schraivogel, Lars M. Steinmetz, Junzo Hamanishi, Masaki Mandai, Matthias Martin Gaida, Theresa Mokry, Johanna Nattenmüller, Oliver Sedlaczek, Nanna Monjé, Roxana Schwab, Annette Hasenburg, Athanasios Mavratzas, Frederik Marmé, Sarah Schott, Niels Halama, Alexandra Pöchmann, Silke A. Grauling-Halama, Alicia Höflich, Aurélie Detavernier, Regina Johanna Boger
| Nature Verified
Abstract Immunotherapy with immune checkpoint blockade (ICB) in epithelial ovarian carcinoma (EOC) shows limited clinical benefit only for a small subset of patients. Overall response rates are low, so that overcoming immunotherapy resistance and improved stratification are key.
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High-Throughput Screening of Combinatorial Immunotherapies with Patient-Specific In Silico Models of Metastatic Colorectal Cancer

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By Jakob Nikolas Kather, Pornpimol Charoentong, Meggy Suarez-Carmona, Esther Herpel
| cancerres.aacrjournals.org
AbstractSolid tumors are rich ecosystems of numerous different cell types whose interactions lead to immune escape and resistance to immunotherapy in virtually all patients with metastatic cancer. Here, we have developed a 3D model of human solid tumor tissue that includes tumor cells, fibroblasts, and myeloid and lymphoid immune cells and can represent over a million cells over clinically relevant timeframes.
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High-throughput screening of combinatorial immunotherapies with patient-specific in silico models of metastatic colorectal cancer

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By Jakob Nikolas Kather, Pornpimol Charoentong, Meggy Suarez-Carmona, Esther Herpel
| cancerres.aacrjournals.org
High-throughput screening of combinatorial immunotherapies with patient-specific in silico models of metastatic colorectal cancer Jakob Nikolas Kather, Pornpimol Charoentong, Meggy Suarez-Carmona, Esther Herpel, Fee Klupp, Alexis Ulrich, Martin Schneider, Inka Zoernig, Tom Luedde, Dirk Jaeger, Jan Poleszczuk and Niels Halama Cancer Res July 2 2018 DOI: 10.1158/0008-5472.CAN-18-1126
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